Cahn M, Chang K, Nguyen P, Butler J
Department of Surgery, University of California, Irvine Medical Center, Orange 92668, USA.
Am J Surg. 1996 Nov;172(5):470-2. doi: 10.1016/S0002-9610(96)00222-X.
Endoscopic ultrasound (EUS) with EUS-guided fine-needle aspiration (EUS-FNA) enables one to visualize the pancreas and surrounding structures and can provide access for FNA of those structures that appear suspicious for tumor.
From 1993 to 1995, 50 patients suspected of having pancreatic cancer underwent EUS/EUS-FNA and abdominal computed tomography (CT). Malignancy was found in 30 (60%) cases, which included 24 (48%) pancreatic adenocarcinomas.
Endoscopic ultrasound/EUS-FNA identified 26 of the 30 malignancies (85%) and 21 of the 24 pancreatic adenocarcinomas (88%), with no false positives. Thirteen of the 24 pancreatic cancer patients had lymph nodes that were sampled with EUS/EUS-FNA. Seven of these 13 patients (62%) were found to have metastatic spread to lymph nodes. Operations were performed on 11 of the pancreatic cancer patients. Of these 11, the 5 that were predicted to be resectable by EUS/EUS-FNA underwent successful resection. Of the 6 predicted to be unresectable, 5 had palliative biliary bypasses, and 1 had a grossly positive margin of resection.
Endoscopic ultrasound/EUS-FNA can identify patients for curative surgical resection. It can also preoperatively identify patients with regional nodal disease for inclusion in appropriately designed clinical trials.
内镜超声（EUS）结合EUS引导下细针穿刺抽吸术（EUS-FNA）能够使医生观察胰腺及其周围结构，并能对那些疑似肿瘤的结构进行细针穿刺抽吸。
1993年至1995年，50例疑似胰腺癌患者接受了EUS/EUS-FNA及腹部计算机断层扫描（CT）检查。30例（60%）患者被发现患有恶性肿瘤，其中包括24例（48%）胰腺腺癌。
内镜超声/EUS-FNA识别出30例恶性肿瘤中的26例（85%）以及24例胰腺腺癌中的21例（88%），无假阳性结果。24例胰腺癌患者中有13例患者的淋巴结通过EUS/EUS-FNA进行了采样。这13例患者中有7例（62%）被发现有淋巴结转移。11例胰腺癌患者接受了手术。在这11例患者中，5例经EUS/EUS-FNA预测可切除的患者成功接受了手术切除。在6例预测不可切除的患者中，5例行姑息性胆肠吻合术，1例手术切缘明显阳性。
内镜超声/EUS-FNA能够识别适合进行根治性手术切除的患者。它还能在术前识别有区域淋巴结疾病的患者，以便纳入适当设计的临床试验。
