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开放性眼球损伤。损伤类型及视力预后的最新情况。

Open-globe injury. Update on types of injuries and visual results.

作者信息

Pieramici D J, MacCumber M W, Humayun M U, Marsh M J, de Juan E

机构信息

Wilmer Ophthalmological Institute, Johns Hopkins Hospital, Baltimore, MD 21287-9228, USA.

出版信息

Ophthalmology. 1996 Nov;103(11):1798-803. doi: 10.1016/s0161-6420(96)30424-7.

DOI:10.1016/s0161-6420(96)30424-7
PMID:8942873
Abstract

PURPOSE

The purpose of the study is to evaluate a recent series of patients who presented with open-globe injuries and to compare this series with a previous series collected at the authors' institution to determine whether prognostic factors or visual outcomes have changed.

METHODS

A retrospective review of 290 eyes of consecutive patients who presented to the Wilmer Ophthalmological Institute with open-globe injuries between December 1985 and January 1993 (group B) was compared with a series of 476 eyes with open-globe injury treated and evaluated at this institute between January 1970 and December 1981 (group A). For comparison, the outcomes evaluated included rates of enucleation and final visual acuity.

RESULTS

Several factors identified previously in group A to correlate with visual outcomes also were found to correlate significantly (P < 0.001) with visual outcome in group B, including: (1) type of injury, (2) location and extent of injury, (3) initial visual acuity, (4) presence of an afferent pupillary defect, (5) lenticular involvement, (6) vitreous hemorrhage, and (7) type of intraocular foreign body. Overall visual outcomes differed significantly between the groups (P = 0.02). The incidence of enucleation was lower in group B (24%) than in group A (30%). However, the percentage of patients who achieved ambulatory visual acuity (5/200) or better was similar in both groups (57%, group A versus 55%, group B).

CONCLUSION

Prognostic factors identified previously proved valid in this recent series. Visual outcomes have improved at this institution in the last 20 years for patients with severe ocular trauma, although visual potential for these patients is still limited.

摘要

目的

本研究旨在评估近期一系列开放性眼球损伤患者,并将该系列与作者所在机构之前收集的系列进行比较,以确定预后因素或视觉结果是否发生了变化。

方法

对1985年12月至1993年1月期间在威尔默眼科研究所就诊的连续性开放性眼球损伤患者的290只眼进行回顾性分析(B组),并与1970年1月至1981年12月期间在该研究所接受治疗和评估的476只开放性眼球损伤眼的系列进行比较(A组)。为进行比较,评估的结果包括眼球摘除率和最终视力。

结果

在A组中先前确定的与视觉结果相关的几个因素在B组中也被发现与视觉结果显著相关(P<0.001),包括:(1)损伤类型,(2)损伤的位置和范围,(3)初始视力,(4)传入性瞳孔缺陷的存在,(5)晶状体受累,(6)玻璃体积血,以及(7)眼内异物类型。两组的总体视觉结果有显著差异(P = 0.02)。B组的眼球摘除率(分别为24%)低于A组(分别为30%)。然而,两组中达到可走动视力(5/200)或更好的患者百分比相似(A组为57%,B组为55%)。

结论

先前确定的预后因素在这一近期系列中被证明是有效的。在过去20年中,该机构严重眼外伤患者的视觉结果有所改善,尽管这些患者的视觉潜力仍然有限。

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