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Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids.

作者信息

Baulieu E E, Robel P

机构信息

INSERM U 33, Le Kremlin-Bicêtre, France.

出版信息

J Endocrinol. 1996 Sep;150 Suppl:S221-39.

PMID:8943804
Abstract
摘要

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Dehydroepiandrosterone and dehydroepiandrosterone sulfate as neuroactive neurosteroids.
J Endocrinol. 1996 Sep;150 Suppl:S221-39.
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Neuroactive steroids modulate HPA axis activity and cerebral brain-derived neurotrophic factor (BDNF) protein levels in adult male rats.神经活性甾体调节成年雄性大鼠的下丘脑-垂体-肾上腺(HPA)轴活性及脑源性神经营养因子(BDNF)蛋白水平。
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Simultaneous determination of dehydroepiandrosterone, its 7-hydroxylated metabolites, and their sulfates in rat brain tissues.同时测定大鼠脑组织中脱氢表雄酮、其7-羟基化代谢物及其硫酸盐。
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The involvement of dehydroepiandrosterone (DHEA) and its sulfate ester (DHEAS) in blocking the therapeutic effect of electroconvulsive shocks in an animal model of depression.脱氢表雄酮(DHEA)及其硫酸酯(DHEAS)在抑郁症动物模型中对电休克治疗效果的阻断作用。
Eur Neuropsychopharmacol. 2005 May;15(3):253-62. doi: 10.1016/j.euroneuro.2004.10.005.

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