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[高度近视患者黄斑裂孔所致视网膜脱离:玻璃体腔内注射纯C3F8的结果]

[Retinal detachment caused by macular holes in patients with severe myopia: results of intravitreal injection of pure C3F8].

作者信息

Pernot A, Fleury J, Bonnet M

机构信息

Clinique Ophtalmologique Universitaire B, UFR Lyon Nord, Hôpital de la Croix-Rousse.

出版信息

J Fr Ophtalmol. 1996;19(8-9):491-5.

PMID:8944130
Abstract

PURPOSE

To evaluate the long-term anatomic and visual results of intravitreal injection of pure C3F8 in the management of retinal detachments due to macular holes in myopic eyes.

MATERIALS AND METHODS

Twenty one highly myopic eyes (19 patients) with retinal detachments due to macular holes were initially managed by intravitreal injection of pure C3F8. The postoperative follow-up ranged from 6,5 to 45 months (median: 27.5 months).

RESULTS

Total retinal reattachment was achieved in 16 eyes (76.2%). Anatomic success was obtained with a single C3F8 injection in 15 eyes, and two injections in one eye. The 5 eyes which failed to reattach after gas injection underwent reoperation using choroidal irritation in the macular area associated with gas injection. The retina was reattached in all eyes. Eleven of the 16 eyes (68.7%) in which the retina was reattached solely with intravitreal gas injection had a nearly normal final near reading visual acuity. In contrast, none of the eyes reattached with the use of choroidal irritation had measurable final visual acuity.

CONCLUSION

The results achieved in the present series of patients confirm that intravitreal injection of pure C3F8 is a valuable alternative in the management of retinal detachments due to macular holes in myopic eyes. We recommend this treatment approach as the initial surgical procedure, since more than half of eyes successfully operated on recover useful central vision.

摘要

目的

评估玻璃体内注射纯C3F8治疗高度近视眼黄斑裂孔性视网膜脱离的长期解剖学和视觉效果。

材料与方法

21只高度近视眼(19例患者)黄斑裂孔性视网膜脱离最初采用玻璃体内注射纯C3F8治疗。术后随访时间为6.5至45个月(中位数:27.5个月)。

结果

16只眼(76.2%)实现视网膜完全复位。15只眼单次注射C3F8获得解剖学成功,1只眼注射两次。气体注射后未能复位的5只眼在黄斑区行脉络膜刺激联合气体注射的再次手术。所有眼视网膜均复位。仅通过玻璃体内气体注射使视网膜复位的16只眼中,11只眼(68.7%)最终近阅读视力接近正常。相比之下,通过脉络膜刺激复位的眼均无可测量的最终视力。

结论

本系列患者的结果证实,玻璃体内注射纯C3F8是治疗高度近视眼黄斑裂孔性视网膜脱离的一种有价值的替代方法。我们推荐这种治疗方法作为初始手术方式,因为超过一半成功手术的眼恢复了有用的中心视力。

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