Oliver K M, Walsh G, Tomlinson A, McFadyen A, Hemenger R P
Department of Vision Sciences, Glasgow Caledonian University, UK.
Ophthalmic Physiol Opt. 1996 Nov;16(6):467-73.
The purpose of this research was to determine if a clinically significant variation in corneal curvature occurs with the menstrual cycle. The EyeSys Corneal Analysis System (CAS) was used to measure corneal curvature of a test group of three normally menstruating female subjects over three cycles and compared with a control group of three males, for three pseudocycles of 28 days. Measurements were taken on days 1, 4, 8, 15 and 22 of each of three menstrual cycles, with four CAS images taken on each day. Four points (along 45, 135, 225 and 315 degrees) were selected for each of rings 1, 3, 6 and 8, and the average curvature for each of these rings was calculated. The results showed that no detectable temporal effect occurred with the menstrual cycle, thus demonstrating that either cyclic variation in corneal topography was too small to be identified by this system or it did not take place.
本研究的目的是确定角膜曲率是否会随着月经周期出现具有临床意义的变化。使用EyeSys角膜分析系统（CAS）对三名正常月经周期的女性受试者进行了三个周期的角膜曲率测量，并与三名男性组成的对照组进行了比较，模拟三个28天的假周期。在三个月经周期的每个周期的第1、4、8、15和22天进行测量，每天拍摄四张CAS图像。在第1、3、6和8环中各选择四个点（沿45、135、225和315度），并计算每个环的平均曲率。结果表明，月经周期未产生可检测到的时间效应，因此表明角膜地形图的周期性变化要么太小以至于该系统无法识别，要么根本没有发生。
