结节性多动脉炎与药物滥用：存在关联吗？

Polyarteritis nodosa and drug abuse: is there a connection?

作者信息

Samuels N, Shemesh O, Yinnon A M, Fisher D, Abraham A S

机构信息

Department of Internal Medicine B, Shaare Zedek Medical Center, Jerusalem, Israel.

出版信息

Postgrad Med J. 1996 Nov;72(853):684-5. doi: 10.1136/pgmj.72.853.684.

DOI:10.1136/pgmj.72.853.684

PMID:8944213

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2398639/

Abstract

Drug abuse has been controversially linked to polyarteritis nodosa. A 28-year-old man with a history of drug abuse with inhaled heroin presented with an enigmatic illness consisting of refractory fever, bilateral pleural effusions, migratory polyarthritis, and a leukaemoid reaction. An abdominal angiography confirmed the diagnosis of polyarteritis nodosa, and treatment with both prednisone and cyclophosphamide resulted in significant clinical and laboratory improvement.

摘要

药物滥用与结节性多动脉炎之间的关联一直存在争议。一名有吸入海洛因药物滥用史的28岁男性，出现了一种难以解释的病症，包括持续性发热、双侧胸腔积液、游走性多关节炎和类白血病反应。腹部血管造影证实了结节性多动脉炎的诊断，泼尼松和环磷酰胺联合治疗使临床症状和实验室检查结果有了显著改善。