Dereure O, Guilhou J J
Department of Dermatology-Phlebology, CHRU Montpellier, France.
Dermatology. 1996;193(3):248-50. doi: 10.1159/000246256.
We describe a new case of a seldom reported subset of fixed drug eruption, the nonpigmenting type. Aside from their fixed nature and their well-demarcated margins, pigmenting and non-pigmenting subsets of fixed drug eruption exhibit well-separated clinical and histological features allowing easy recognition. The precise physiopathology is currently unknown in both conditions, but a delayed hypersensitivity mechanism is likely. The nature of the inducing drugs of the nonpigmenting eruption is discussed.
我们描述了一例鲜少报道的固定性药疹亚型——非色素沉着型的新病例。除了其固定性和边界清晰外，固定性药疹的色素沉着型和非色素沉着型表现出截然不同的临床和组织学特征，易于识别。目前这两种情况的确切病理生理学尚不清楚，但可能存在迟发型超敏反应机制。本文还讨论了非色素沉着型药疹诱发药物的性质。
