Mochloulis G, Irving R M, Grant H R, Miller R F
Department of Otolaryngology, University College London Hospitals (NHS) Trust, London, UK.
J Laryngol Otol. 1996 Nov;110(11):1034-7. doi: 10.1017/s0022215100135698.
Over a period of 10 years 17 human immunodeficiency virus(HIV)-infected patients with laryngeal Kaposi's sarcoma were seen and treated at University College London Hospitals. All patients had advanced HIV disease. Their presentation was with symptoms of upper airway obstruction in the majority of cases and the diagnosis was made by fibreoptic examination of the larynx. Biopsy was associated with brisk haemorrhage in one patient, who required a temporary tracheostomy, and was not performed in the other 16 cases. The commonest site of laryngeal involvement was the supraglottis in 11 patients, with glottic lesions noted in eight patients: subglottic lesions were seen in only three. Treatment of laryngeal Kaposi's sarcoma was, in general, conservative, five patients received low dose radiotherapy to the larynx and 10 were treated with systemic chemotherapy for disseminated Kaposi's sarcoma. Laryngeal Kaposi's sarcoma did not contribute to patient mortality.
在10年期间，伦敦大学学院医院诊治了17例感染人类免疫缺陷病毒（HIV）且患有喉卡波西肉瘤的患者。所有患者的HIV病情都已发展到晚期。大多数患者表现为上呼吸道梗阻症状，通过喉镜纤维检查做出诊断。活检时，有1例患者出现大量出血，需要临时气管切开术，其他16例患者未进行活检。喉受累最常见的部位是会厌上区，有11例患者；声门病变见于8例患者；声门下病变仅见于3例。一般而言，喉卡波西肉瘤的治疗较为保守，5例患者接受了喉部低剂量放疗，10例患者因播散性卡波西肉瘤接受了全身化疗。喉卡波西肉瘤未导致患者死亡。
