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狭窄血流中磁共振相速度测量的准确性。

The accuracy of magnetic resonance phase velocity measurements in stenotic flow.

作者信息

Siegel J M, Oshinski J N, Pettigrew R I, Ku D N

机构信息

George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta 30332-0405, USA.

出版信息

J Biomech. 1996 Dec;29(12):1665-72.

PMID:8945670
Abstract

Nuclear magnetic resonance (MR) can be used to measure velocities in fluid flow using the technique of phase velocity mapping. Advantages of MR velocimetry include the simultaneous mapping of the entire flow field through a non-contacting, magnetic window. The phase velocity mapping technique assumes that velocity is constant over the measurement time (typically around 10 ms). For many fluid flows, this assumption is not valid. The current study showed that MR phase velocity measurements of velocity through stenotic flow can be in error by over 100% immediately upstream and downstream of the stenosis throat and by 20% far downstream of the throat in comparison with laser Doppler anemometer measurements taken at the same location. Highly turbulent flow also led to significant errors in velocity measurement. These errors can be attributed to several sources including low signal-to-noise ratio, additional phase shifts due to non-constant velocities, and non-stationary transit-time effects. Velocity measurement errors could be reduced to under 30% at all measurement locations through the use of MR sequences with high signal-to-noise ratios, low echo times, and thick slices.

摘要

核磁共振(MR)可利用相速度映射技术来测量流体流动中的速度。MR测速法的优点包括通过非接触式磁窗口同时映射整个流场。相速度映射技术假定在测量时间内(通常约为10毫秒)速度是恒定的。对于许多流体流动而言,这一假设并不成立。当前研究表明,与在同一位置进行的激光多普勒风速仪测量相比,通过狭窄流的MR相速度测量在狭窄喉部上游和下游紧邻处的速度误差可能超过100%,在喉部下游远处的误差为20%。高度湍流的流动也会导致速度测量出现显著误差。这些误差可归因于多个来源,包括低信噪比、因速度不恒定导致的额外相移以及非平稳渡越时间效应。通过使用具有高信噪比、低回波时间和厚切片的MR序列,可将所有测量位置的速度测量误差降低至30%以下。

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