Skinner G R, Davies J, Ahmad A, McLeish P, Buchan A
Department of Infection, Medical School, University of Birmingham, U.K.
J Infect. 1996 Nov;33(3):163-7. doi: 10.1016/s0163-4453(96)92129-5.
An outbreak of herpes rugbiorum involved nine players including the scrum half and the full back. The infection was characterized by significant constitutional upset with decreased levels of general fitness and match performance for 1-4 months following the outbreak; one player had herpetic lesions on his right eyelid and corneum. Every infected player, 15 non-infected players and five sociosexual contacts received two vaccinations with intracellular subunit vaccine NFU. Ac. HSV-1 (S-MRC5). None of the players or contacts developed cutaneous herpetic recurrence during a follow-up period of 3 years; the player with ocular disease had one recurrence at 30 months following the original episode. These findings encourage consideration of prophylactic or post-exposure vaccination of participants in rugby or other contact sports with this or other appropriate herpes simplex vaccine.
一起鲁氏疱疹疫情涉及9名球员，包括一名传锋和一名全卫。感染的特征是在疫情爆发后的1至4个月内，出现明显的全身不适，一般健康水平和比赛表现下降；一名球员的右眼睑和角膜出现疱疹性病变。每一位受感染球员、15名未受感染球员以及5名性接触者都接种了两剂细胞内亚单位疫苗NFU。Ac. HSV-1（S-MRC5）。在3年的随访期内，没有一名球员或接触者出现皮肤疱疹复发；患有眼部疾病的球员在初次发作30个月后复发了一次。这些发现促使人们考虑对橄榄球或其他接触性运动的参与者使用这种或其他合适的单纯疱疹疫苗进行预防性或暴露后接种。
