Youn J, Cox T A, Allingham R R, Shields M B
Joseph M. Bryan Glaucoma Clinic, Duke University Eye Center, Durham, North Carolina, USA.
J Glaucoma. 1996 Dec;5(6):390-4.
To determine the factors associated with visual acuity loss following transscleral Nd:YAG cyclophotocoagulation (TYC).
The authors retrospectively studied 479 patients followed for a mean of 22 months after the initial TYC in one eye and analyzed the data with univariate and multivariate analysis for the factors associated with visual acuity loss. Data analyzed included age, race, sex, preoperative intraocular pressure (IOP) and visual acuity, type of glaucoma, total energy per treatment, number of retreatments, final IOP, and duration of follow-up.
The preoperative factors associated with visual acuity loss after TYC as determined by both univariate and multivariate analysis were neovascular glaucoma (p = 0.001, odds ratio = 2.80) and black race (p = 0.044, odds ratio = 1.67). Postoperative hypotony and follow-up of > 6 months were also associated with visual acuity loss (p < 0.001, odds ratio = 6.68 and p = 0.046, odds ratio = 2.61, respectively).
Transscleral Nd:YAG cyclophotocoagulation is associated with a greater risk of visual acuity loss in patients with neovascular glaucoma and in the black population. Postoperative hypotony is associated with a poor visual outcome, whereas the association with longer follow-up duration suggests that other factors, related to the patient's underlying disease, are also significant factors.
确定经巩膜Nd:YAG睫状体光凝术（TYC）后视力丧失的相关因素。
作者回顾性研究了479例患者，这些患者单眼首次接受TYC治疗后平均随访22个月，并对与视力丧失相关的因素进行单因素和多因素分析。分析的数据包括年龄、种族、性别、术前眼压（IOP）和视力、青光眼类型、每次治疗的总能量、再次治疗次数、最终眼压和随访时间。
单因素和多因素分析确定的TYC后与视力丧失相关的术前因素为新生血管性青光眼（p = 0.001，比值比 = 2.80）和黑人种族（p = 0.044，比值比 = 1.67）。术后低眼压和随访时间>6个月也与视力丧失相关（分别为p < 0.001，比值比 = 6.68和p = 0.046，比值比 = 2.61）。
经巩膜Nd:YAG睫状体光凝术在新生血管性青光眼患者和黑人人群中导致视力丧失的风险更高。术后低眼压与视力预后不良相关，而与较长随访时间的关联表明，与患者基础疾病相关的其他因素也是重要因素。
