Bell G W, Britto J A
Pinderfields Hospital NHS Trust, Wakefield.
Dent Update. 1995 Nov;22(9):383-5.
Malignant melanoma arises from melanocytes, dendritic cells of neural crest origin. Melanocytes occur within the basal layers of the epidermis, mucous membranes, retina and uveal structures of the eye and the meninges. Rarely, they may also occur in the bladder, adrenal medulla and ovaries. These melanomas metastasise widely and metastases in the oral mucosa have been seen in about 3% of patients with cutaneous melanoma, and can complicate the healing of extraction sites. This paper presents a case of malignant melanoma of the mandible.
恶性黑色素瘤起源于神经嵴来源的树突状细胞黑素细胞。黑素细胞存在于表皮的基底层、黏膜、视网膜、眼的葡萄膜结构以及脑膜中。极少数情况下,它们也可能出现在膀胱、肾上腺髓质和卵巢中。这些黑色素瘤广泛转移,皮肤黑色素瘤患者中约3%会出现口腔黏膜转移,并且会使拔牙部位的愈合复杂化。本文介绍了一例下颌骨恶性黑色素瘤病例。