甲状腺细胞外谷胱甘肽过氧化物酶：甲状腺激素合成的潜在调节因子。
Thyroidal extracellular glutathione peroxidase: a potential regulator of thyroid-hormone synthesis.
作者信息
Howie A F, Walker S W, Akesson B, Arthur J R, Beckett G J
机构信息
Cellular Endocrinology Unit, University Department of Clinical Biochemistry, Royal Infirmary, Edinburgh, U.K.
出版信息
Biochem J. 1995 Jun 15;308 ( Pt 3)(Pt 3):713-7. doi: 10.1042/bj3080713.
Abstract
Human thyrocytes were found to synthesize and secrete the selenoenzyme extracellular glutathione peroxidase (E-GPX), a process which was controlled by the Ca2+/phosphoinositol second-messenger cascade. The potential involvement of thyroidal E-GPX in the regulation of thyroid-hormone synthesis and in the protection of the thyrocyte from peroxidative damage is discussed.
摘要
人们发现人类甲状腺细胞能合成并分泌硒酶——细胞外谷胱甘肽过氧化物酶（E-GPX），这一过程受Ca2+/磷酸肌醇第二信使级联反应的控制。文中讨论了甲状腺E-GPX在甲状腺激素合成调节及保护甲状腺细胞免受过氧化损伤方面的潜在作用。
Zotero 插件