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复发性胃食管反流的外科治疗

[Surgical treatment of recurrent gastroesophageal reflux].

作者信息

Iascone C, Moraldi A, Barreca M, Stipa S

机构信息

I Istituto di Clinica Chirurgica, Università degli Studi di Roma La Sapienza.

出版信息

Ann Ital Chir. 1995 Sep-Oct;66(5):615-20.

PMID:8948798
Abstract

From 1972 to 1994, 66 patients underwent 67 Belsey MK IV antireflux repairs in our unit. Fifteen of the 67 patients or 22% had previously undergone antireflux surgery (10 hiatal repairs and 5 antireflux repairs). Obstructive symptoms were present in one patient who had previously undergone a Nissen fundoplication whereas all other patients presented recurrent reflux. There were no operative complications and only one hospital mortality (6.6%). Long-term results were good-to-excellent in 62% of all patients and fair in 15% of all patients; failures constituted 23% of all cases and were due to recurrent reflux symptoms. In the literature of the last 20 years, two groups can be identified, one group consisting of 142 patients treated surgically after unsuccessful Nissen fundoplication, the other group consisting of 438 patients who underwent 580 operations due to failure of the more common antireflux procedures used today. Recurrent reflux was the most frequent cause of failure in both groups (48% in the first and 58% in the second group). With respect to obstructing symptoms (26% and 32% respectively), these were due to a tight wrap in those patients who underwent a Nissen fundoplication and to peptic stenoses in those patients who underwent other surgical procedures. In 25% of patients who underwent a Nissen fundoplication, the cause of failure was the so-called "Slipped Nissen", responsible for both obstructing symptoms and reflux. In 60% of patients treated for failure following a Nissen fundoplication, the same surgical procedure was used. In the second group, only 20% of all patients underwent a Nissen fundoplication while 20% underwent esophageal resections and another 20% other antireflux surgical procedures. The differences in mortality and morbidity in the two groups (0-2% vs 0-12% and 0-33% vs 21-73%) are probably related to a higher incidence of the thoracic approach in the second group. Good-to-excellent results were achieved in 60-100% of patients treated for failure after a Nissen fundoplication and in 58-60% in those patients treated for failure of other various surgical procedures.

摘要

1972年至1994年期间,我院66例患者接受了67次Belsey MK IV抗反流修复术。67例患者中有15例(22%)此前曾接受过抗反流手术(10例裂孔修复术和5例抗反流修复术)。1例曾接受过nissen胃底折叠术的患者出现梗阻症状,而其他所有患者均表现为反流复发。无手术并发症,仅1例患者死亡(6.6%)。所有患者中,62%的患者长期效果良好至极佳,15%的患者效果一般;失败病例占所有病例的23%,原因是反流症状复发。在过去20年的文献中,可以分为两组,一组由142例nissen胃底折叠术失败后接受手术治疗的患者组成,另一组由438例因当今常用的抗反流手术失败而接受580次手术的患者组成。两组中,反流复发都是最常见的失败原因(第一组为48%,第二组为58%)。关于梗阻症状(分别为26%和32%),接受nissen胃底折叠术的患者是由于包裹过紧,而接受其他手术的患者是由于消化性狭窄。在接受nissen胃底折叠术的患者中,25%的失败原因是所谓的“滑脱nissen”,导致梗阻症状和反流。在因nissen胃底折叠术失败而接受治疗的患者中,60%采用了相同的手术方法。在第二组中,所有患者中只有20%接受了nissen胃底折叠术,20%接受了食管切除术,另外20%接受了其他抗反流手术。两组的死亡率和发病率差异(0 - 2%对0 - 12%以及0 - 33%对21 - 73%)可能与第二组开胸手术的发生率较高有关。nissen胃底折叠术失败后接受治疗的患者中,60 - 100%取得了良好至极佳的效果,而因其他各种手术失败接受治疗的患者中,这一比例为58 - 60%。

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