Egea J M, Tor J, Muga R, Roca J, Rodríguez R, Navío M, Rey-Joly C
Unidad de Desintoxicación, Hospital Universitario Germans Trias i Pujol, Barcelona.
Med Clin (Barc). 1996 Jan 27;106(3):87-90.
The differences in the rates of HIV infection in intravenous drug addicts according to the age of onset of drug consumption, sex and length of intake were evaluated.
The study sample was made up of 650 intravenous drug addicts (535 males and 115 females) admitted to a Hospital Detoxication Unit over 7 years (1987-1993). Of all these patients HIV serology and a questionnaire related to sociodemographic variables and drug consumption (age, sex, year of onset of intravenous drug intake, length of addiction and year of admission) were obtained.
The rate of HIV infection for any length of addiction was higher in females than in males with this difference being significant for a length of addiction of less than 24 months (p = 0.03). The greater the age of onset in the use of intravenous drugs the lower the rate of HIV infection (p < 0.0001). In addiction times of less than 24 months the subjects who began drug consumption at an earlier age than the mean (19 years) presented significantly higher HIV infection rates (p = 0.04).
Among the intravenous drug consumers in the area of Barcelona, Spain subgroups may be found: those who enter the consumption of intravenous drugs early and women, demonstrating high rates of HIV seroprevalence from the onset of their addiction.
根据吸毒起始年龄、性别和吸毒时长,评估静脉注射吸毒者中艾滋病毒感染率的差异。
研究样本由7年间(1987 - 1993年)入住一家医院戒毒科的650名静脉注射吸毒者组成(535名男性和115名女性)。获取了所有这些患者的艾滋病毒血清学检测结果以及一份与社会人口统计学变量和吸毒情况(年龄、性别、静脉注射吸毒起始年份、成瘾时长和入院年份)相关的问卷。
无论成瘾时长如何,女性的艾滋病毒感染率均高于男性,且成瘾时长小于24个月时这种差异具有统计学意义(p = 0.03)。静脉注射吸毒起始年龄越大,艾滋病毒感染率越低(p < 0.0001)。在成瘾时长小于24个月的人群中,开始吸毒年龄早于平均年龄(19岁)的受试者艾滋病毒感染率显著更高(p = 0.04)。
在西班牙巴塞罗那地区的静脉注射吸毒者中,可以发现一些亚组:那些较早开始静脉注射吸毒的人群以及女性,他们从成瘾开始就表现出较高的艾滋病毒血清阳性率。