Bouscarat F, Belaich S
Service de dermatologie, Hôpital Bichat, Paris.
Rev Prat. 1996 Sep 1;46(13):1629-35.
Among the different targets affected by immunodeficiency, skin is at the first line. Infections are the most frequent causes of cutaneous manifestations in immunocompromised subjects. They are primitive or secondary cutaneous infections occurring during disseminated disease. Skin manifestations may reveal the systemic disease. Primary or secondary bacterial, viral, fungic, and parasitic mucocutaneous diseases are often atypical, extensive and frequently follow chronical course. These peculiar presentations makes diagnosis difficult. The knowledge of the clinical pleomorphism of skin infections in immunocompromised subjects is essential. All doubtfull lesions must lead to histological and microbiological study. Diagnosis delay may increase the risk of dissemination resulting in morbidity and mortality.
在免疫缺陷影响的不同靶器官中，皮肤处于第一线。感染是免疫功能低下患者皮肤表现的最常见原因。它们是在播散性疾病期间发生的原发性或继发性皮肤感染。皮肤表现可能揭示全身性疾病。原发性或继发性细菌、病毒、真菌和寄生虫性黏膜皮肤疾病通常是非典型的、广泛的，且常呈慢性病程。这些特殊表现使得诊断困难。了解免疫功能低下患者皮肤感染的临床多形性至关重要。所有可疑病变都必须进行组织学和微生物学检查。诊断延迟可能会增加播散风险，从而导致发病和死亡。
