Hogan Molly T
Division of Emergency Services, Harborview Medical Center, University of Washington School of Medicine, Box 359702, 325 9th Avenue, Seattle, WA 98104, USA.
Dermatol Clin. 2006 Oct;24(4):473-95, vi. doi: 10.1016/j.det.2006.06.010.
With diminished and dysregulated cell-mediated immunity, HIV-infected individuals are susceptible to a myriad of skin infections. These infections include the conditions encountered in immunocompetent patients, as well as infections seen almost exclusively in the setting of HIV infection. The HIV/AIDS pandemic has made some previously rare infections more prominent. Although antiretroviral therapy has been helpful in relieving the burden of cutaneous infections in HIV-infected patients, it does not prevent all opportunistic infections in the skin and also has created new dilemmas.
由于细胞介导的免疫功能减弱和失调,感染HIV的个体易患多种皮肤感染。这些感染包括免疫功能正常患者所患的疾病,以及几乎仅在HIV感染情况下出现的感染。艾滋病毒/艾滋病大流行使一些以前罕见的感染更加突出。尽管抗逆转录病毒疗法有助于减轻HIV感染患者皮肤感染的负担,但它并不能预防皮肤的所有机会性感染,还带来了新的难题。