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[非洲黑人的动脉高血压。50例患者的临床及超声心动图研究]

[Arterial hypertension in black Africans. Clinical and echographic study in 50 patients].

作者信息

Abassade P, Lamour P, Iung B, Delbechi G, Guiomard A

机构信息

Hôpital Max Fourestier, Nanterre.

出版信息

Presse Med. 1996 Sep 21;25(27):1234-8.

PMID:8949734
Abstract

OBJECTIVES

Clinical and electrocardiographic and echocardiographic data were collected in 50 black Africans with hypertension to study modifications in left ventricular geometry.

METHODS

Thirty men and 20 women with hypertension (mean age 40.9 +/- 10.2 years) who had recently immigrated from Africa were included in the study. Parameters recorded were: systolic and diastolic pressures, body mass index (BMI = weight/height2); ECG; echocardiography (36 patients): end diastolic septal and posterior wall thickness, left ventricle diameter, left ventricle mass (LVM) and relative wall thickness.

RESULTS

Systolic and diastolic pressures and BMI were 169 +/- 24 mmHg, 105 +/- 14 mmHg and 26.7 +/- 3.9 kg/m2). LVM was 129 +/- 41 g/m2 (Normal < 134 g/m2) in men and 113 +/- 35 g/m2 (Normal = 110 g/m2) in women. Concentric remodeling was found in 8 patients (LVM = normal, relative wall thickness > or = 0.45), concentric left ventricle hypertrophy in 10 (LVM > normal, relative wall thickness > or = 0.45), excentric left ventricular hypertrophy in 6 (LVM > normal, relative wall thickness < 0.45), asymmetric septal hypertrophy in 4 and normal echocardiogram in 8. There was a negative correlation between age and end diastolic left ventricle diameter (r = -0.34, p < 0.05) and age and end systolic ventricle diameter (r = -0.74, p < 0.05). There was a positive correlation between body surface and septal thickness (r = 0.34, p < 0.05), posterior wall thickness (r = 0.56, relative wall p < 0.001), and relative wall thickness (r = 0.45, p = 0.05).

CONCLUSION

This population of young subjects with hypertension showed a high prevalence of modifications in left ventricular geometry with predominant concentric modeling with (8/36) and without (10/36) left ventricle hypertrophy.

摘要

目的

收集50名患有高血压的非洲黑人的临床、心电图和超声心动图数据,以研究左心室几何形态的改变。

方法

本研究纳入了30名男性和20名女性高血压患者(平均年龄40.9±10.2岁),他们最近从非洲移民而来。记录的参数包括:收缩压和舒张压、体重指数(BMI=体重/身高²);心电图;超声心动图(36例患者):舒张末期室间隔和后壁厚度、左心室直径、左心室质量(LVM)和相对壁厚度。

结果

收缩压和舒张压以及BMI分别为169±24 mmHg、105±14 mmHg和26.7±3.9 kg/m²。男性LVM为129±41 g/m²(正常<134 g/m²),女性为113±35 g/m²(正常=110 g/m²)。8例患者出现向心性重塑(LVM正常,相对壁厚度≥0.45),10例出现向心性左心室肥厚(LVM>正常,相对壁厚度≥0.45),6例出现离心性左心室肥厚(LVM>正常,相对壁厚度<0.45),4例出现不对称性室间隔肥厚,8例超声心动图正常。年龄与舒张末期左心室直径之间存在负相关(r=-0.34,p<0.05),年龄与收缩末期心室直径之间也存在负相关(r=-0.74,p<0.05)。体表面积与室间隔厚度(r=0.34,p<0.05)、后壁厚度(r=0.56,p<0.001)和相对壁厚度(r=0.45,p=0.05)之间存在正相关。

结论

这群患有高血压的年轻受试者显示出左心室几何形态改变的高患病率,主要为向心性重塑,伴有(8/36)和不伴有(10/36)左心室肥厚。

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