Baldo Marcelo Perim, Gonçalves Mauer A, Capingana Daniel P, Magalhães Pedro, da Silva Amilcar B Tomé, Mill José Geraldo
Department of Pathophysiology, Montes Claros State University-UNIMONTES, Av Rui Braga, Vila Mauricéia, 39401-089, Montes Claros, MG, Brazil.
Department of Physiology, Faculty of Medicine, University Agostinho Neto, Luanda, Angola.
High Blood Press Cardiovasc Prev. 2018 Sep;25(3):283-289. doi: 10.1007/s40292-018-0267-y. Epub 2018 Jun 28.
African-Americans present higher prevalence of left ventricular hypertrophy (LVH) when compared with white populations. However, there is a lack of information about the prevalence and determinants of LVH in black individuals living in Africa.
A cross-sectional study was performed with a non-probabilistic sample comprised of 609 University workers from Angola/Africa, describing the prevalence of LVH and the determinants of left ventricular mass. Echocardiographic measurements were performed and left ventricular mass was indexed to body surface area. Systolic and diastolic blood pressures were measured, along with anthropometric and clinical variables.
Chamber diameter and wall thickness were higher in men compared to women. Additionally, LVM was higher in men (114.2 ± 36 vs 98.4 ± 31.9, P < 0.001), and the overall prevalence of LVH in black Angolans was 41.1%, which tended to be higher in women (44.5 vs 37.4%, P = 0.096). In men, systolic blood pressure and BMI were independently associated with LVM, while age, systolic blood pressure and waist circumference were associated with LVM in women.
In summary, blood pressure levels were the main determinants of LVH in black Africans, although different anthropometric variables showed mild influence in LVM. Our data suggests that LVH prevalence and determinants in black Africans are similar to that reported for African-Americans.
与白人相比，非裔美国人左心室肥厚（LVH）的患病率更高。然而，关于生活在非洲的黑人中LVH的患病率及其决定因素的信息却很匮乏。
对来自非洲安哥拉的609名大学工作人员组成的非概率样本进行了一项横断面研究，描述LVH的患病率和左心室质量的决定因素。进行了超声心动图测量，并将左心室质量指数化到体表面积。测量了收缩压和舒张压，以及人体测量和临床变量。
男性的心室直径和壁厚高于女性。此外，男性的左心室质量更高（114.2±36 vs 98.4±31.9，P<0.001），安哥拉黑人中LVH的总体患病率为41.1%，女性患病率略高（44.5%对37.4%，P=0.096）。在男性中，收缩压和体重指数与左心室质量独立相关，而在女性中，年龄、收缩压和腰围与左心室质量相关。
总之，血压水平是非洲黑人LVH的主要决定因素，尽管不同的人体测量变量对左心室质量有轻微影响。我们的数据表明，非洲黑人中LVH的患病率及其决定因素与非裔美国人的报道相似。
