Auffarth G U, Tsao K, Wesendahl T A, Sugita A, Apple D J
Storm Eye Institute, Department of Ophthalmology and Pathology, Medical University of South Carolina, Charleston, USA.
Acta Ophthalmol Scand. 1996 Oct;74(5):463-7. doi: 10.1111/j.1600-0420.1996.tb00600.x.
Pseudoexfoliation syndrome is an important risk factor in cataract surgery. We examined decentration of posterior chamber intraocular lenses in a series of 24 autopsy eyes with pseudoexfoliation syndrome that had undergone cataract surgery and intraocular lens implantation. The results were compared to a control group of 25 normal autopsy eyes that matched the pseudoexfoliation collection for age distribution, implant duration and further anatomical parameters. The mean lens decentration in all pseudoexfoliation eyes (0.75 +/- 0.38 mm) was significantly higher than in the control group (0.40 +/- 0.29 mm) (p = 0.0008). Analysis of subgroups with symmetrical bag/bag fixated intraocular lenses showed a significantly higher decentration in the pseudoexfoliation group (p = 0.04). The main reason for decentration was a decentration of the entire capsular bag in pseudoexfoliative eyes (p = 0.001), which was related to zonular weakness and damage. The results indicate that in patients with pseudoexfoliation syndrome alternative fixation sites, like sulcus or transscleral fixation, should also be considered.
假性剥脱综合征是白内障手术中的一个重要危险因素。我们检查了一系列24只患有假性剥脱综合征且已接受白内障手术和人工晶状体植入的尸眼后房型人工晶状体的偏心情况。将结果与25只正常尸眼的对照组进行比较，该对照组在年龄分布、植入时间和其他解剖参数方面与假性剥脱样本相匹配。所有假性剥脱眼的晶状体平均偏心度（0.75±0.38毫米）显著高于对照组（0.40±0.29毫米）（p = 0.0008）。对采用对称囊袋/囊袋固定人工晶状体的亚组分析显示，假性剥脱组的偏心度显著更高（p = 0.04）。偏心的主要原因是假性剥脱眼中整个囊袋的偏心（p = 0.001），这与悬韧带薄弱和损伤有关。结果表明，对于患有假性剥脱综合征的患者，也应考虑如沟内固定或经巩膜固定等替代固定部位。
