Vissum Corporation, Alicante, Spain.
Eye (Lond). 2013 Jul;27(7):795-801; quiz 802. doi: 10.1038/eye.2013.95. Epub 2013 Jun 14.
To study the predisposing factors for late in-the-bag intraocular lens (IOL) dislocation and to analyze the outcomes after explantation surgery.
In this retrospective multicentre study, 61 eyes were enrolled. The main inclusion criterion was in-the-bag spontaneous IOL dislocation after uneventful phacoemulsification cataract extraction. Only eyes with serious dislocation that required IOL explantation were eligible. Follow-up after explantation surgery of at least 3 months was required. Exclusion criteria were complicated cataract surgery, out-of-the-bag IOL dislocation, and dislocations that occurred in the first year after the cataract surgery. The main outcome measures were predisposing factors for dislocation, interval between cataract surgery and dislocation, surgical treatment at the time of explantation, preoperative and postoperative corrected distance visual acuity (CDVA), and postoperative complications.
High myopia was detected in 12 cases (19.7%) and it was the main predisposing factor. Mean time interval from cataract surgery to dislocation was 7.5 (SD 5.2) years. The dislocated in-the-bag IOL was replaced with a scleral fixated IOL (36.1%), angle-supported anterior chamber IOL (31.1%), sulcus repositioning (18%), or posterior chamber iris sutured IOL (4.9%). Finally, 9.8% of the patients were left aphakic. Mean CDVA improved significantly after surgery (P=0.005). Final CDVA of 20/40 or better was achieved in 29 cases (47.5%).
High myopia was the main risk factor for late in-the-bag IOL dislocation. Surgical treatment significantly improved the CDVA in our sample and was associated with a low complication rate.
研究眼内人工晶状体(IOL)迟发性袋内脱位的易患因素,并分析取出术后的结果。
在这项回顾性多中心研究中,共纳入 61 只眼。主要纳入标准为白内障超声乳化吸除术后无并发症的眼内自发性 IOL 脱位。仅纳入需要取出 IOL 的严重脱位眼。要求取出术后随访至少 3 个月。排除标准为复杂白内障手术、眼外 IOL 脱位以及白内障手术后 1 年内发生的脱位。主要观察指标为脱位的易患因素、白内障手术与脱位之间的间隔时间、取出时的手术治疗、术前和术后矫正视力(CDVA)以及术后并发症。
发现高度近视 12 例(19.7%),为主要易患因素。白内障手术后至脱位的平均时间间隔为 7.5(SD 5.2)年。脱位的袋内 IOL 被更换为巩膜固定 IOL(36.1%)、角支撑前房 IOL(31.1%)、巩膜缝线固定术(18%)或后房型虹膜缝线固定术(4.9%)。最终,9.8%的患者为无晶状体眼。术后 CDVA 显著提高(P=0.005)。29 例(47.5%)最终获得 20/40 或更好的 CDVA。
高度近视是迟发性袋内 IOL 脱位的主要危险因素。手术治疗显著提高了我们样本中的 CDVA,且并发症发生率较低。