Cormio L, Nisén H, Ruutu M, Selvaggi F P
Chair of Urology, R School of Medicine, University of Bari, Italy.
Ann Chir Gynaecol. 1996;85(3):247-50.
The aim of this study was to verify the efficacy and safety of intracavernous injection of etilefrine hydrochloride in the prevention of pharmacologically induced prolonged erection. Two hundred rigid erections due to diagnostic pharmacological stimulation were treated with immediate intracavernous injection of 5 to 10 mg etilefrine hydrochloride. Penile response and general side effects after the injection were recorded. Patients were interviewed after 1-2 weeks about possible side effects. Detumescence occurred within 10 minutes in 194 (97%) cases. In the remaining six (3%), detumescence occurred after cavernous aspiration and additional injection of 5 mg etilefrine. Thirteen patients (6.5%) had transitory palpitations. None of the patients had hypertensive crisis, cardiac arrythmia or ischaemic events. Intracavernous injection of etilefrine is effective and safe in preventing prolonged erection after diagnostic pharmacological stimulation.
本研究的目的是验证海绵体内注射盐酸乙苯福林在预防药物诱导的持续性勃起方面的有效性和安全性。对200例因诊断性药理刺激导致的阴茎勃起坚硬的患者，立即海绵体内注射5至10毫克盐酸乙苯福林进行治疗。记录注射后的阴茎反应和一般副作用。1至2周后对患者进行访谈，了解可能出现的副作用。194例（97%）患者在10分钟内阴茎消肿。其余6例（3%）患者在海绵体抽吸并额外注射5毫克乙苯福林后阴茎消肿。13例患者（6.5%）出现短暂心悸。所有患者均未发生高血压危象、心律失常或缺血性事件。海绵体内注射乙苯福林在预防诊断性药理刺激后出现的持续性勃起方面有效且安全。
