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[局限性前列腺癌的根治性前列腺切除术]

[Radical prostatectomy for localized prostate cancer].

作者信息

Arakawa S, Hara I, Miyake H, Taguchi I, Yamada Y, Gotoh A, Ueno K, Matsui T, Fujisawa M, Eto H, Gohji K, Okada H, Kamidono S

机构信息

Department of Urology, Kobe University School of Medicine.

出版信息

Hinyokika Kiyo. 1996 Oct;42(10):811-5.

PMID:8951480
Abstract

We studied 81 patients who underwent radical prostatectomy for prostate cancer. Ten, 57 and 14 patients were clinically diagnosed with stage T1, T2 and T3, respectively. Pelvic lymph node dissection was performed prior to prostatectomy in all cases. The neurovascular bundle was preserved in 21 patients. Compared with pathological stage, the accuracy rate of clinical staging in T1, T2 and T3 was 40, 46 and 64% respectively. Approximately half of the patients clinically diagnosed with stage T2 were pT3. The positive rate of lymph node in pT2 and pT3 was 3.3 and 37% respectively, showing a marked difference between these two pathological stages. The 3-year non-recurrence rates were 89% in patients with pT2 and 79% in pT3. In the well differentiated carcinoma group, no patients had recurrence for up to 3 years. All of the patients with infiltration (INF) gamma showed recurrence within 3 years. Fifty-five patients had no problem on urination post-operatively, while the other 23 patients had a mild or moderate incontinence and the remaining 3 patients had a small urine stream. Regarding erectile potency, 4 out of 18 evaluable patients were potent.

摘要

我们研究了81例接受前列腺癌根治术的患者。其中,10例、57例和14例患者临床诊断分别为T1期、T2期和T3期。所有病例均在前列腺切除术前进行了盆腔淋巴结清扫。21例患者保留了神经血管束。与病理分期相比,T1期、T2期和T3期临床分期的准确率分别为40%、46%和64%。临床诊断为T2期的患者中约一半为pT3期。pT2期和pT3期淋巴结阳性率分别为3.3%和37%,这两个病理分期之间存在显著差异。pT2期患者3年无复发率为89%,pT3期为79%。在高分化癌组中,3年内无患者复发。所有浸润(INF)γ的患者在3年内均出现复发。55例患者术后排尿无问题,23例患者有轻度或中度尿失禁,其余3例患者尿流细小。关于勃起功能,18例可评估患者中有4例功能正常。

相似文献

1
[Radical prostatectomy for localized prostate cancer].[局限性前列腺癌的根治性前列腺切除术]
Hinyokika Kiyo. 1996 Oct;42(10):811-5.
2
[Early results following radical prostatectomy in patients with capsule invasion, seminal vesicle infiltration and micrometastases].[前列腺被膜侵犯、精囊浸润及微转移患者根治性前列腺切除术后的早期结果]
Urologe A. 1990 Mar;29(2):91-5.
3
[Results of 15 years of radical prostatectomy].[前列腺癌根治术15年的结果]
Urologe A. 1995 May;34(3):225-30.
4
[Clinical outcome of radical prostatectomy and pelvic lymph node dissection].根治性前列腺切除术及盆腔淋巴结清扫术的临床结果
Hinyokika Kiyo. 1995 Nov;41(11):867-71.
5
Influence of microinvasion of the capsule and/or micrometastasis of regional lymph nodes on disease free survival after radical prostatectomy.前列腺包膜微浸润和/或区域淋巴结微转移对根治性前列腺切除术后无病生存期的影响。
Ann Urol (Paris). 1994;28(4):196-201.
6
Extended pelvic lymphadenectomy in patients undergoing radical prostatectomy: high incidence of lymph node metastasis.接受根治性前列腺切除术患者的扩大盆腔淋巴结清扫术:淋巴结转移发生率高。
J Urol. 2002 Apr;167(4):1681-6.
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No difference in six-year biochemical failure rates with or without pelvic lymph node dissection during radical prostatectomy in low-risk patients with localized prostate cancer.在局限性前列腺癌的低风险患者中,根治性前列腺切除术期间进行或不进行盆腔淋巴结清扫,六年生化复发率无差异。
Urology. 2004 Mar;63(3):528-31. doi: 10.1016/j.urology.2003.09.064.
8
The extent of lymphadenectomy for pTXNO prostate cancer does not affect prostate cancer outcome in the prostate specific antigen era.在前列腺特异性抗原时代,pTXNO前列腺癌的淋巴结清扫范围不影响前列腺癌的预后。
J Urol. 2005 Apr;173(4):1121-5. doi: 10.1097/01.ju.0000155533.93528.4c.
9
Limited pelvic lymph node dissection at the time of radical prostatectomy does not affect 5-year failure rates for low, intermediate and high risk prostate cancer: results from CaPSURE.前列腺癌根治术时行有限盆腔淋巴结清扫术不影响低、中、高危前列腺癌的5年失败率:CaPSURE研究结果
J Urol. 2007 Feb;177(2):526-29; discussion 529-30. doi: 10.1016/j.juro.2006.09.053.
10
A preoperative nomogram identifying decreased risk of positive pelvic lymph nodes in patients with prostate cancer.一种用于识别前列腺癌患者盆腔淋巴结转移风险降低的术前列线图。
J Urol. 2003 Nov;170(5):1798-803. doi: 10.1097/01.ju.0000091805.98960.13.