Arakawa S, Hara I, Miyake H, Taguchi I, Yamada Y, Gotoh A, Ueno K, Matsui T, Fujisawa M, Eto H, Gohji K, Okada H, Kamidono S
Department of Urology, Kobe University School of Medicine.
Hinyokika Kiyo. 1996 Oct;42(10):811-5.
We studied 81 patients who underwent radical prostatectomy for prostate cancer. Ten, 57 and 14 patients were clinically diagnosed with stage T1, T2 and T3, respectively. Pelvic lymph node dissection was performed prior to prostatectomy in all cases. The neurovascular bundle was preserved in 21 patients. Compared with pathological stage, the accuracy rate of clinical staging in T1, T2 and T3 was 40, 46 and 64% respectively. Approximately half of the patients clinically diagnosed with stage T2 were pT3. The positive rate of lymph node in pT2 and pT3 was 3.3 and 37% respectively, showing a marked difference between these two pathological stages. The 3-year non-recurrence rates were 89% in patients with pT2 and 79% in pT3. In the well differentiated carcinoma group, no patients had recurrence for up to 3 years. All of the patients with infiltration (INF) gamma showed recurrence within 3 years. Fifty-five patients had no problem on urination post-operatively, while the other 23 patients had a mild or moderate incontinence and the remaining 3 patients had a small urine stream. Regarding erectile potency, 4 out of 18 evaluable patients were potent.
我们研究了81例接受前列腺癌根治术的患者。其中,10例、57例和14例患者临床诊断分别为T1期、T2期和T3期。所有病例均在前列腺切除术前进行了盆腔淋巴结清扫。21例患者保留了神经血管束。与病理分期相比,T1期、T2期和T3期临床分期的准确率分别为40%、46%和64%。临床诊断为T2期的患者中约一半为pT3期。pT2期和pT3期淋巴结阳性率分别为3.3%和37%,这两个病理分期之间存在显著差异。pT2期患者3年无复发率为89%,pT3期为79%。在高分化癌组中,3年内无患者复发。所有浸润(INF)γ的患者在3年内均出现复发。55例患者术后排尿无问题,23例患者有轻度或中度尿失禁,其余3例患者尿流细小。关于勃起功能,18例可评估患者中有4例功能正常。