Barch D M, Cohen J D, Servan-Schreiber D, Steingard S, Cohen J D, Steinhauer S S, van Kammen D P
Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA.
J Abnorm Psychol. 1996 Nov;105(4):592-601. doi: 10.1037//0021-843x.105.4.592.
Semantic priming in word pronunciation was examined at 5 stimulus onset asynchronies (SOAs) in 75 medicated and 25 unmedicated people with schizophrenia (SCZ) and in 10 depressed and 28 normal controls. At SOAs < 950 ms, SCZ displayed priming similar to that of normal and depressed controls. At the 950-ms SOA, SCZ displayed less priming than controls. Medication dosage, but not conceptual disorganization scores, was positively associated with priming at SOAs < 950 ms. These results suggest that prior reports of enhanced priming in schizophrenia may have been confounded by methodological problems and that automatic priming processes operate normally in SCZ. The failure of SCZ to display significant priming at the 950-ms SOA is consistent with a hypothesized disturbance in higher level processes.
在75名服用药物的精神分裂症患者（SCZ）、25名未服用药物的精神分裂症患者以及10名抑郁症患者和28名正常对照者中，研究了5种刺激起始时间间隔（SOA）下单词发音中的语义启动效应。在SOA小于950毫秒时，精神分裂症患者表现出与正常对照者和抑郁症对照者相似的启动效应。在950毫秒的SOA时，精神分裂症患者表现出的启动效应低于对照者。在SOA小于950毫秒时，药物剂量而非概念紊乱得分与启动效应呈正相关。这些结果表明，先前关于精神分裂症中启动效应增强的报告可能受到了方法学问题的混淆，并且自动启动过程在精神分裂症患者中正常运作。精神分裂症患者在950毫秒的SOA时未能表现出显著的启动效应，这与更高层次过程中假设的干扰一致。
