Aboyans V, Lacroix P, Cornu E, Virot P, Labrousse F, Ostyn E, Christides C, Laskar M
Service de CTCV et angiologie, CHRU Dupuytren, Limoges.
Arch Mal Coeur Vaiss. 1996 Oct;89(10):1297-300.
The search for a cancer is part of the classical investigation of unexplained venous thrombosis. Arterial thrombosis associated with neoplasia is more rare. The authors report two cases in which arterial thrombosis was the final event of their malignant disease. The first case had abacterial thrombotic endocarditis and disseminated intravascular coagulation at the origin of multiple thrombotic complications. The initially unknown cancer was a pancreatic adenocarcinoma. The second case presented with acute occlusion of the iliac artery after ablation of a malignant melanoma. Despite embolectomy with a Fogarty catheter and effective anticoagulation, the thrombosis recurred several times at the same site. The clinical features and the mechanisms of these two cases suggestive of Trousseau's syndrome are discussed.
寻找癌症是不明原因静脉血栓形成经典检查的一部分。与肿瘤相关的动脉血栓形成较为罕见。作者报告了两例动脉血栓形成是其恶性疾病最终事件的病例。第一例最初出现无菌性血栓性心内膜炎和弥漫性血管内凝血，继而引发多种血栓并发症。最初未知的癌症是胰腺腺癌。第二例在恶性黑色素瘤切除术后出现髂动脉急性闭塞。尽管使用Fogarty导管进行了栓子切除术并进行了有效的抗凝治疗，但血栓仍在同一部位多次复发。本文讨论了这两例提示Trousseau综合征的临床特征及机制。
