Mahon B D, Green B K, Von Oppell U O
Westmead Hospital, Sydney, Australia.
J Heart Valve Dis. 1996 Nov;5 Suppl 3:S324-8.
After implanting 19mm and 21mm Sorin pericardial aortic valves (AVR) in 35 women over the age of 60 years, it was our clinical impression that these patients had an unduly high incidence of residual valve stenosis. A retrospective comparison of our experience with this valve and the 19mm St. Jude mechanical AVR in a similar group of 26 patients, operated during the same period (October 1987 to July 1994), was carried out. In comparison to the 19mm St. Jude valve, the 19 mm Sorin Pericardial valve was associated with significant residual stenosis in elderly women despite similar body surface areas. This prosthesis/patient mismatch was not eliminated by the use of a 21 mm Sorin pericardial valve. Although the Sorin pericardial valves was associated with a reduced incidence of thromboembolism and anticoagulation related hemorrhage, it had a significantly increased risk of permanent valve related morbidity and mortality. As a result if this experience we have discontinued our use of the Sorin pericardial valve.
在为35名60岁以上女性植入19毫米和21毫米的索林心包主动脉瓣（AVR）后，我们的临床印象是这些患者残余瓣膜狭窄的发生率过高。我们对同期（1987年10月至1994年7月）手术的26名类似患者使用该瓣膜的经验与19毫米圣犹达机械主动脉瓣进行了回顾性比较。与19毫米圣犹达瓣膜相比，尽管体表面积相似，但19毫米索林心包瓣膜在老年女性中与显著的残余狭窄相关。使用21毫米索林心包瓣膜并未消除这种假体/患者不匹配的情况。尽管索林心包瓣膜与血栓栓塞和抗凝相关出血的发生率降低有关，但其永久性瓣膜相关发病和死亡的风险显著增加。基于这一经验，我们已停止使用索林心包瓣膜。
