Takahashi H, Satoh T, Sakio H
Second Department of Anesthesiology, Dokkyo University School of Medicine, Tochigi.
Masui. 1996 Nov;45(11):1380-3.
A 43-year-old female with HELLP syndrome underwent an emergency caesarean section under general anesthesia. Anesthesia was induced by fentanyl and thiopental with oxygen inhalation. Bolus injection of nicardipine was used to treat hypertensive crisis during operation. Continuous intravenous infusion of prostaglandin E1 was started after delivery to normalize arterial blood pressure. After surgery, both the patient and her baby were discharged uneventfully. It is suggested that a suitable dosage of fentanyl is effective without causing serious side effects for neonate. Prostaglandin E1 may have cytoprotective action in vital organs, such as the liver and the kidney, and may stabilize the arterial blood pressure.
一名患有HELLP综合征的43岁女性在全身麻醉下接受了急诊剖宫产手术。麻醉诱导采用芬太尼和硫喷妥钠并吸入氧气。术中静脉推注尼卡地平治疗高血压危象。产后开始持续静脉输注前列腺素E1以使动脉血压恢复正常。术后,患者及其婴儿均顺利出院。提示合适剂量的芬太尼有效且不会对新生儿造成严重副作用。前列腺素E1可能对肝脏和肾脏等重要器官具有细胞保护作用,并可能稳定动脉血压。