Furuya A, Matsukawa T, Kumazawa T
Department of Anesthesia, Yamanashi Medical University.
Masui. 1996 Nov;45(11):1413-6.
We report a rare case of coronary artery spasm during burr hole opening for craniotomy in a patient with no past history of coronary artery disease. A 52-year-old man was scheduled for the removal of the brain tumor under general anesthesia. Anesthesia was induced with fentanyl, thiamylal, and vecuronium, and maintained with sevoflurane plus nitrous oxide in oxygen. When burr holes were made for the craniotomy, the heart rate decreased suddenly and the ECG in lead II demonstrated the elevation of the ST segment (0.3mV). After about 1 min, the ST segment elevation returned to normal without any treatment. The dura mater was rather tense with inspection. Despite many reported cases of coronary artery spasm during general anesthesia, coronary artery spasm during burr hole opening for craniotomy has not been reported. In the present case, since the heart rate decreased and the elevation of the ST segment occurred at the time of the burr hole opening for craniotomy, the activated vagal tone reflex induced by the stimulation of the dura mater seemed to have caused the coronary artery spasm.
我们报告了一例在开颅钻孔过程中发生冠状动脉痉挛的罕见病例,该患者既往无冠状动脉疾病史。一名52岁男性计划在全身麻醉下切除脑肿瘤。麻醉诱导使用芬太尼、硫喷妥钠和维库溴铵,并用七氟醚加一氧化二氮和氧气维持。当进行开颅钻孔时,心率突然下降,II导联心电图显示ST段抬高(0.3mV)。约1分钟后,未经任何治疗,ST段抬高恢复正常。检查时硬脑膜相当紧张。尽管有许多关于全身麻醉期间冠状动脉痉挛的报道病例,但开颅钻孔过程中发生冠状动脉痉挛尚未见报道。在本病例中,由于在开颅钻孔时心率下降且ST段抬高,硬脑膜刺激诱发的迷走神经张力反射激活似乎导致了冠状动脉痉挛。