Iwasaki Soushi, Furuse Shingo, Watanabe Masanori, Yamauchi Masanori, Asano Makoto, Ooiwa Hitoshi, Yamakage Michiaki, Namiki Akiyoshi
Department of Anesthesia, Ohji General Hospital, Tomakomai 053-8506.
Masui. 2004 Jan;53(1):59-62.
A 59-year-old man without a history of ischemic heart disease underwent elective laparoscopic cholecystectomy under general anesthesia with epidural anesthesia. About 15 min after pneumoperitoneum had been achieved, the patient developed ST elevation and hypotension. Vagal stimulation resulting from stretching peritoneum, the procedure and epidural anesthesia are thought to have induced vasospasm. The ST segment became normal after interruption of CO2 insufflation. A postoperative coronary artery angiogram showed normal coronary arteries, but diffuse coronary artery spasm was seen after intracoronary injection of acetylcholine. The patient was discharged on nitrates. Patients with gall bladder stones sometimes have coronary risk factors of obesity, hyperlipidemia and hyperglycemia. Careful attention should also be given to patients who do not have a history of coronary disease.
一名59岁无缺血性心脏病病史的男性在全身麻醉联合硬膜外麻醉下接受择期腹腔镜胆囊切除术。气腹建立约15分钟后,患者出现ST段抬高和低血压。腹膜牵拉、手术操作及硬膜外麻醉引起的迷走神经刺激被认为诱发了血管痉挛。停止二氧化碳气腹后ST段恢复正常。术后冠状动脉造影显示冠状动脉正常,但冠状动脉内注射乙酰胆碱后可见弥漫性冠状动脉痉挛。患者出院时服用硝酸盐类药物。胆囊结石患者有时存在肥胖、高脂血症和高血糖等冠心病危险因素。对于无冠心病病史的患者也应予以密切关注。