Steinberg M S
Department of Molecular Biology, Princeton University, Princeton, New Jersey, 08544, USA.
Dev Biol. 1996 Dec 15;180(2):377-88. doi: 10.1006/dbio.1996.0312.
My purpose here is to provide brief historical overviews of three related subjects conceptually fundamental to the broader subject of "cell adhesion in development." These subjects are (1) the evolution of our present understanding of how animal cells cohere; (2) the question of what principles underlie the ability of embryonic cell populations to organize themselves into anatomically correct structures; and (3) the ongoing effort to understand the origins of the "recognition specificity" evinced in the latter phenomenon. Because this review must be brief, it is not possible to mention all of the significant advances, many of which will be referenced in a recent more detailed review of this subject (Grunwald, 1991). For the same reason, the important work on cell adhesion in nonvertebrate systems is not included.
我在此的目的是简要回顾三个在“发育中的细胞黏附”这一更广泛主题中概念上至关重要的相关主题的历史概况。这些主题分别是：（1）我们目前对动物细胞如何黏附在一起的理解的演变；（2）胚胎细胞群体能够将自身组织成解剖学上正确结构的能力背后的原理问题；（3）为理解后一种现象中表现出的“识别特异性”的起源而正在进行的努力。由于这篇综述必须简短，所以不可能提及所有重大进展，其中许多将在最近一篇关于该主题的更详细综述（Grunwald，1991年）中引用。出于同样的原因，非脊椎动物系统中关于细胞黏附的重要工作未被纳入。
