Bittner E, Chendrasekhar A, Pillai S, Timberlake G A
Department of Surgery, West Virginia University School of Medicine, Morgantown, USA.
Am Surg. 1996 Dec;62(12):1038-41.
Body positioning during mechanical ventilation for acute lung injury has not been studied in a detailed manner. We evaluated the relationship between oxygenation, compliance, and body position during mechanical ventilation of patients with acute lung injury (ALI). Sixteen patients on mechanical ventilation with a diagnosis of ALI (partial pressure of oxygen/fraction of inspired oxygen <300 and no clinical evidence of congestive heart failure) were prospectively studied. Each patient was placed in a supine position followed by a 30 degrees head elevation and a 45 degrees head elevation. Data obtained in each position (after a 45-60 minute equilibration time) included static pulmonary compliance and partial pressure of oxygen from arterial blood gas sampling. Oxygenation is not improved and compliance is adversely affected by upright body positioning as compared to the supine position in patients receiving mechanical ventilation for ALI.
急性肺损伤患者机械通气期间的体位尚未得到详细研究。我们评估了急性肺损伤（ALI）患者机械通气期间氧合、顺应性与体位之间的关系。对16例诊断为ALI（氧分压/吸入氧分数<300且无充血性心力衰竭临床证据）并接受机械通气的患者进行了前瞻性研究。每位患者先取仰卧位，然后将头部抬高30度和45度。在每个体位（经过45 - 60分钟平衡时间后）获得的数据包括静态肺顺应性和动脉血气采样中的氧分压。与接受ALI机械通气的患者仰卧位相比，直立体位并未改善氧合，反而对顺应性产生不利影响。
