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甲状腺肿瘤细针穿刺活检后梗死:28例病例回顾

Post-fine-needle biopsy infarction of thyroid neoplasms: a review of 28 cases.

作者信息

Kini S R

机构信息

Department of Pathology, Henry Ford Hospital, Detroit, MI 48202, USA.

出版信息

Diagn Cytopathol. 1996 Sep;15(3):211-20. doi: 10.1002/(SICI)1097-0339(199609)15:3<211::AID-DC7>3.0.CO;2-J.

DOI:10.1002/(SICI)1097-0339(199609)15:3<211::AID-DC7>3.0.CO;2-J
PMID:8955603
Abstract

This report describes 28 cases of thyroids which had undergone infarction following fine-needle aspiration (FNA) biopsy procedure. Their cytologic diagnoses included 15 Hürthle cell tumors, eight papillary carcinomas, and five follicular neoplasms. Nine patients also had large-needle biopsy performed within 3 wk of FNA biopsy, three of which showed infarction and one had no surgical follow-up. Surgery was performed on 27 patients within 7 to 90 days. All 27 cases showed partial to total infarction. Histological and cytologic diagnoses were not in accordance in 12 cases, either due to complete fibrosis (two cases), obscuring of histologic details (four cases), or failure to recognize the thin rim of neoplastic tissue at the periphery, by pathologists unaware of the cytologic diagnoses (six cases). Fine-needle biopsy results should be made available to the surgical pathologists handling the surgically excised thyroid specimen. Also, partial or complete infarction must initiate careful examination, so as not to miss any neoplasms.

摘要

本报告描述了28例在细针穿刺(FNA)活检术后发生梗死的甲状腺病例。其细胞学诊断包括15例许特莱细胞肿瘤、8例乳头状癌和5例滤泡性肿瘤。9例患者在FNA活检后3周内还进行了粗针活检,其中3例显示梗死,1例未进行手术随访。27例患者在7至90天内接受了手术。所有27例均显示部分至完全梗死。12例组织学和细胞学诊断不一致,原因包括完全纤维化(2例)、组织学细节模糊(4例)或病理学家未意识到细胞学诊断而未能识别周边薄的肿瘤组织边缘(6例)。应将细针活检结果提供给处理手术切除甲状腺标本的外科病理学家。此外,部分或完全梗死必须引发仔细检查,以免漏诊任何肿瘤。

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