Department of Radiology, Busan Paik Hospital, Inje University College of Medicine, Busan 47392, Korea.
Department of Pathology, Busan Paik Hospital, Inje University College of Medicine, Busan 47392, Korea.
Korean J Radiol. 2018 Jan-Feb;19(1):158-166. doi: 10.3348/kjr.2018.19.1.158. Epub 2018 Jan 2.
None of the previous studies have investigated the interval change in ultrasonography (US) features of solid thyroid nodules (STNs) after US-guided fine-needle aspiration (US-FNA). This study aimed to assess the prevalence and characteristics of US interval changes in STNs after US-FNA.
This study included 257 STNs in 257 patients in whom thyroid US and initial US-FNA had been performed by two radiologists from January 2015 to June 2015. One of the radiologists performed single needle puncture in all cases, whereas the other radiologist used double or triple needle punctures. Follow-up US examinations were performed after 12.0 ± 6.0 months. We evaluated the prevalence and characteristics of post-FNA US interval changes through a retrospective analysis. In addition, multiple factors were correlated with post-FNA US interval changes.
The number of needle punctures was one (n = 91), two (n = 163), and three (n = 3). Of the 257 STNs (mean diameter, 11.9 mm) in 257 patients, 35 (13.6%) showed an interval change in US features on follow-up US. Among them, 17 STNs (6.6%) showed newly developed malignant US features, including hypoechogenicity (n = 5), microcalcifications (n = 2), a spiculated margin (n = 4), hypoechogenicity with a spiculated margin (n = 5), and microcalcifications with non-parallel orientation (n = 1). Between patients who showed presence and absence of US interval changes, there were no significant differences in patient age, sex, nodule size, dichotomization, and location, Korean Thyroid Imaging Reporting and Data System categorization after FNA, practitioners involved, number of needle punctures, cytological findings, and interval between FNA and US follow-up ( > 0.05).
Awareness of US interval changes after US-FNA of STNs may be helpful for the management of STNs.
之前的研究均未探讨甲状腺实性结节（STN）在超声引导下细针抽吸活检（US-FNA）后的超声特征的间隔变化。本研究旨在评估 STN 在 US-FNA 后的超声间隔变化的发生率和特征。
本研究纳入了 2015 年 1 月至 2015 年 6 月期间由 2 位放射科医生进行甲状腺超声和初始 US-FNA 的 257 例 257 例 STN 患者。所有病例均由一位放射科医生进行单次穿刺，而另一位放射科医生采用双针或三针穿刺。在 12.0 ± 6.0 个月后进行了随访超声检查。我们通过回顾性分析评估了 FNA 后 US 间隔变化的发生率和特征。此外，还对多种因素与 FNA 后 US 间隔变化的相关性进行了分析。
穿刺针数为 1 针（n = 91）、2 针（n = 163）和 3 针（n = 3）。在 257 例患者的 257 个 STN（平均直径为 11.9mm）中，有 35 个（13.6%）在随访超声中出现了 US 特征的间隔变化。其中，17 个 STN（6.6%）出现了新的恶性 US 特征，包括低回声（n = 5）、微钙化（n = 2）、刺状边缘（n = 4）、低回声伴刺状边缘（n = 5）和非平行取向的微钙化（n = 1）。在出现和未出现 US 间隔变化的患者之间，患者年龄、性别、结节大小、二分类、位置、FNA 后的韩国甲状腺影像报告和数据系统分类、参与的医生、穿刺针数、细胞学发现以及 FNA 与 US 随访之间的间隔无显著差异（> 0.05）。
了解 STN 在 US-FNA 后的 US 间隔变化可能有助于 STN 的管理。
