Bokhout B, Hofman F X, van Limbeek J, Kramer G J, Prahl-Andersen B
Department of Orthodontics, Academic Centre for Dentistry Amsterdam (ACTA), The Netherlands.
Caries Res. 1997;31(1):8-12. doi: 10.1159/000262366.
The incidence of dental caries in the primary dentition was determined in Dutch cleft lip and/or palate children (n = 81) and in children without a congenital malformation (n = 77). In the oral cleft group the incidence of dental caries (0.037; 95% CI 0.031-0.046) was significantly higher than in the control group (0.004; 95% CI 0.002-0.007) with a crude incidence rate ratio of 9.3. Adjusted for oral hygiene, oral cleft yielded a rate ratio (relative risk) of approximately 3.5 (95% CI 1.35-9.28) in the multivariate analysis. Dental caries occurred in 25 children with an oral cleft (30.9%) and in 5 control children (6.5%). All types of teeth were affected in the oral cleft group while in the control group dental caries only occurred in maxillary incisors and second molars. The highest incidence of dental caries was found in the teeth beside the oral cleft and in the primary molars of the oral cleft group.
对荷兰唇腭裂儿童(n = 81)和无先天性畸形的儿童(n = 77)的乳牙龋齿发病率进行了测定。唇腭裂组的龋齿发病率(0.037;95%可信区间0.031 - 0.046)显著高于对照组(0.004;95%可信区间0.002 - 0.007),粗发病率比为9.3。在多变量分析中,经口腔卫生因素调整后,唇腭裂导致的发病率比(相对风险)约为3.5(95%可信区间1.35 - 9.28)。25名唇腭裂儿童(30.9%)患龋齿,5名对照儿童(6.5%)患龋齿。唇腭裂组所有类型的牙齿均受影响,而对照组龋齿仅发生在上颌切牙和第二磨牙。唇腭裂组中,唇腭裂旁的牙齿和乳牙磨牙的龋齿发病率最高。