一名患有Castleman病的13岁女孩的铁治疗抵抗性小细胞贫血。
Iron therapy resistant microcytic anaemia in a 13-year-old girl with Castleman disease.
作者信息
De Heer-Groen T A, Prakken A B, Bax N M, van Dijken P J
机构信息
Hospital Centre Apeldoorn, The Netherlands.
出版信息
Eur J Pediatr. 1996 Dec;155(12):1015-7. doi: 10.1007/BF02532521.
UNLABELLED
We describe the case history of a 13-year-old girl with chronic fatigue and prolonged microcytic anaemia. She received oral iron since the age of 11 but failed to respond to it. Laboratory studies revealed elevated C-reactive protein and hypergammaglobulinaemia. A large solitary mesenterial lymph node could be demonstrated by ultrasonography and CT. A diagnosis of Castleman disease was suspected and confirmed histologically. After surgical removal of the lymphoma the patient recovered completely.
CONCLUSION
Castleman disease should be considered in cases of chronic fatigue, unexplained fever, microcytic anaemia and hypergammaglobulinaemia.
未标注
我们描述了一名13岁患有慢性疲劳和持续性小细胞贫血女孩的病史。她从11岁起就接受口服铁剂治疗，但对此无反应。实验室检查显示C反应蛋白升高和高球蛋白血症。超声检查和CT可显示一个大的孤立肠系膜淋巴结。怀疑为Castleman病，并经组织学确诊。手术切除淋巴瘤后，患者完全康复。
结论
对于慢性疲劳、不明原因发热、小细胞贫血和高球蛋白血症的病例，应考虑Castleman病。
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