Angiofollicular lymph node transformation in Hodgkin's lymphoma.

We present four examples of lymph nodes that have Hodgkin's disease between nodules of angiofollicular hyperplasia, three hyaline-vascular and one plasma cell in type, suggesting the concurrence of the lymphoma with Castleman's disease. Angiofollicular hyperplasia is claimed to be an immune derangement, and its presence in Hodgkin's disease may represent such a situation.