Hirvonen J, Huttunen P
Department of Forensic Medicine, University of Oulu, Finland.
Int J Legal Med. 1996;109(3):143-6. doi: 10.1007/BF01369675.
Postmortem changes in serum noradrenaline and adrenaline concentrations in adrenectomised rabbits and in human sudden death cases were measured with HPLC in order to obtain information of the usefulness of these biogenic amines as indicators of antemortem stress. It appeared that serum concentrations increased with time postmortem, except for adrenaline in the adrenectomised rabbits. The values varied considerably between individuals in both materials. It is concluded that postmortem assays of serum catecholamines cannot be used in practice to demonstrate antemortem stress, although this would theoretically be a promising approach, e.g., in cases of suffocation. So far there seems to be no reliable and conclusive method for estimating short lasting antemortem stress in individual forensic cases.
为了获取这些生物胺作为生前应激指标的有用信息，采用高效液相色谱法测定了肾上腺切除兔和人类猝死病例血清中去甲肾上腺素和肾上腺素的死后变化。结果显示，除肾上腺切除兔的肾上腺素外，血清浓度随死后时间增加。两种材料中个体间的值差异很大。结论是，血清儿茶酚胺的死后检测在实践中不能用于证明生前应激，尽管从理论上讲这是一种有前景的方法，例如在窒息案件中。到目前为止，在个体法医案件中似乎还没有可靠且结论性的方法来估计短暂的生前应激。
