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银屑病:病理生理学与口腔表现

Psoriasis: pathophysiology and oral manifestations.

作者信息

Zhu J F, Kaminski M J, Pulitzer D R, Hu J, Thomas H F

机构信息

Department of Pediatric Dentistry, University of Texas Health Science Center at San Antonio 78284-7888, USA.

出版信息

Oral Dis. 1996 Jun;2(2):135-44. doi: 10.1111/j.1601-0825.1996.tb00214.x.

DOI:10.1111/j.1601-0825.1996.tb00214.x
PMID:8957926
Abstract

Psoriasis is a chronic, remitting and relapsing inflammatory skin disorder with a strong genetic predisposition. Psoriasis affects 1-3% of the world's population in their early lives representing a disabling condition with significant social and economic impact. Despite a great deal of research on the etiology and tissue destruction mechanisms, the disease is not well understood. The purpose of this paper is to provide current information from the literature with a special focus on oral manifestations. The major signs and symptoms presented in the oral environment of a psoriasis patient may include geographic tongue, fissure tongue, gingival and/or mucosal lesions. Inflammatory temporomandibular joint lesions have been reported in less than 5% of psoriasis patients. Multiple treatment strategies, be they topical or systemic, have been applied to these patients for symptom relief but not for cure.

摘要

银屑病是一种具有强烈遗传易感性的慢性、缓解与复发交替的炎症性皮肤病。银屑病在人们早年时影响全球1%-3%的人口,是一种造成残疾的疾病,具有重大的社会和经济影响。尽管对其病因和组织破坏机制进行了大量研究,但该疾病仍未被充分了解。本文旨在提供文献中的最新信息,特别关注口腔表现。银屑病患者口腔环境中出现的主要体征和症状可能包括地图舌、沟纹舌、牙龈和/或黏膜病变。据报道,不到5%的银屑病患者存在炎性颞下颌关节病变。已经对这些患者应用了多种治疗策略,无论是局部治疗还是全身治疗,以缓解症状,但无法治愈。

相似文献

1
Psoriasis: pathophysiology and oral manifestations.银屑病:病理生理学与口腔表现
Oral Dis. 1996 Jun;2(2):135-44. doi: 10.1111/j.1601-0825.1996.tb00214.x.
2
Oral psoriasis: report of six new cases.口腔银屑病:6例新病例报告。
J Oral Pathol Med. 1995 Jan;24(1):42-5. doi: 10.1111/j.1600-0714.1995.tb01128.x.
3
Oral manifestations of psoriasis. Clinical presentation and management.银屑病的口腔表现。临床表现与管理
N Y State Dent J. 2012 Apr;78(3):14-8.
4
Psoriasiform lesions of the oral mucosa (with emphasis on "ectopic geographic tongue").
Oral Surg Oral Med Oral Pathol. 1974 Jun;37(6):872-88. doi: 10.1016/0030-4220(74)90440-x.
5
Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review.地图舌与银屑病:临床、组织病理学、免疫组织化学及遗传学相关性——文献综述
An Bras Dermatol. 2016 Jul-Aug;91(4):410-21. doi: 10.1590/abd1806-4841.20164288.
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[Normal variations in lingual soft tissue].[舌部软组织的正常变异]
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[Changes in the oral mucosa in psoriasis pustulosa generalisata].[泛发性脓疱型银屑病的口腔黏膜变化]
Hautarzt. 1987 Jul;38(7):419-21.
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[Reiter's syndrome oral manifestations].
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Oral lesions in patients with psoriasis: a controlled study.银屑病患者的口腔病变:一项对照研究。
Cutis. 1992 May;49(5):339-44.
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Geographic tongue (migrant glossitis) and psoriasis.地图舌(游走性舌炎)与银屑病。
Minerva Stomatol. 2001 Jun;50(6):213-7.

引用本文的文献

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The Role of Genetics in Human Oral Health: A Systematic-Narrative Review.遗传学在人类口腔健康中的作用:一项系统叙述性综述。
Dent J (Basel). 2025 Mar 16;13(3):133. doi: 10.3390/dj13030133.
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A Diagnostic Challenge of Oral Psoriasis in a Pediatric Patient: A Case Report and Review of the Literature.一名儿科患者口腔银屑病的诊断挑战:病例报告及文献综述
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Oral and Maxillo-Facial Manifestations of Systemic Diseases: An Overview.全身疾病的口腔颌面部表现:综述
Medicina (Kaunas). 2021 Mar 16;57(3):271. doi: 10.3390/medicina57030271.
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An Intriguing Case of Ectopic Benign Migratory Glossitis Resembling Secondary Syphilis: A Case Report.一例类似二期梅毒的异位良性游走性舌炎的罕见病例:病例报告
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Palatal Erythema with Histological Psoriasiform Pattern: An Enigmatic Oral Finding Shared by a Range of Conditions.腭部红斑伴组织学银屑病样模式:一系列疾病共有的神秘口腔表现。
Head Neck Pathol. 2020 Dec;14(4):1111-1116. doi: 10.1007/s12105-020-01127-1. Epub 2020 Jan 27.
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Diagnosis of Lingual Atrophic Conditions: Associations with Local and Systemic Factors. A Descriptive Review.舌萎缩状况的诊断:与局部及全身因素的关联。一项描述性综述。
Open Dent J. 2016 Nov 16;10:619-635. doi: 10.2174/1874210601610010619. eCollection 2016.
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Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review.地图舌与银屑病:临床、组织病理学、免疫组织化学及遗传学相关性——文献综述
An Bras Dermatol. 2016 Jul-Aug;91(4):410-21. doi: 10.1590/abd1806-4841.20164288.
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The Differential Diagnosis of Desquamative Gingivitis: Review of the Literature and Clinical Guide for Dental Undergraduates.剥脱性龈炎的鉴别诊断:文献综述及牙科本科生临床指南
J Int Oral Health. 2015;7(Suppl 1):88-92.
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Temporomandibular Disorders in Psoriasis Patients with and without Psoriatic Arthritis: An Observational Study.伴或不伴银屑病关节炎的银屑病患者的颞下颌关节紊乱:一项观察性研究
Int J Med Sci. 2015 Apr 26;12(4):341-8. doi: 10.7150/ijms.11288. eCollection 2015.
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Suprabasal overexpression of the hsRPB7 gene in psoriatic epidermis as identified by a reverse transcriptase-polymerase chain reaction differential display model comparing psoriasis plaque tissue with peritonsillar mucosa.通过逆转录聚合酶链反应差异显示模型,将银屑病斑块组织与扁桃体周黏膜进行比较,确定银屑病表皮中hsRPB7基因的基底层上表达上调。
Am J Pathol. 2001 Feb;158(2):367-72. doi: 10.1016/s0002-9440(10)63978-8.