Nakao M, Kodama T, Sasaki M, Kuroda K
Department of Thoracic Surgery, Hirakata City Hospital, Osaka, Japan.
Kyobu Geka. 1996 Dec;49(13):1069-73.
A case of amylase-producing lung cancer is reported. A 58-year-old man was admitted to our hospital because of abnormal shadow on chest X-rays. Transbronchial lung biopsy showed adenocarcinoma at the right upper lobe. Amylase levels were elevated to 915 IU/l in the serum and 960 IU/l in urine. Amylase isozyme pattern identified "salivary-type" amylase. Right upper lobectomy was performed. Both serum and urine, amylase levels were decreased within normal limits after operation. Enzyme labeled immunoperoxidase method on this specimen proved that tumor cells were producing amylase ectopically.
报告了一例产生淀粉酶的肺癌病例。一名58岁男性因胸部X光片出现异常阴影而入住我院。经支气管肺活检显示右上叶为腺癌。血清淀粉酶水平升至915 IU/l,尿淀粉酶水平升至960 IU/l。淀粉酶同工酶谱鉴定为“唾液型”淀粉酶。实施了右上叶切除术。术后血清和尿液中的淀粉酶水平均降至正常范围。对该标本采用酶标记免疫过氧化物酶法证明肿瘤细胞在异位产生淀粉酶。