Yoshino H, Shibata S, Arita M
Department of Neurology, National institute of Neurology and Psychiatry, Kohnodai Hospital.
Rinsho Shinkeigaku. 1996 Aug;36(8):990-2.
High-titer IgM antibody against sulfated glucuronyl paragloboside (SGPG) was detected in a case of Guillain-Barré syndrome. The patient recovered rapidly by the treatment with double filtration plasmapheresis and the anti-SGPG antibody was not detected on the 40th day of illness. Facial nerve palsy, however, lasted until the 6th month of illness. Anti-SGPG antibody might have the important role in the pathologic mechanisms of Guillain-Barré syndrome in this case.
在1例吉兰-巴雷综合征患者中检测到高效价抗硫酸化葡糖醛酸副球蛋白(SGPG)抗体。患者通过双重过滤血浆置换治疗迅速康复,在患病第40天时未检测到抗SGPG抗体。然而,面神经麻痹一直持续到患病第6个月。在该病例中,抗SGPG抗体可能在吉兰-巴雷综合征的病理机制中起重要作用。