Sakai H, Yanai T, Yoshida K, Iwasaki T, Fujioka H, Ota J, Isowa K, Masegi T
Department of Veterinary Pathology, Gifu University, Japan.
J Vet Med Sci. 1996 Nov;58(11):1113-5. doi: 10.1292/jvms.58.11_1113.
A rare case of ameloblastoma with prominent stromal ossification in an 8-year-old female dog was studied. A bony mass recurred rapidly in the right mandible at the first molar region. Histopathologic examination revealed the lesion to be an atypical variant of ameloblastoma. Epithelial cells showed marked cell atypia, and mitotic figures were rather common. The collagenous stroma was abundant, with prominent formation of bone trabecular rimmed by active osteoblasts. The tumor was highly proliferative and aggressive, and thought to be malignant in nature.
对一例8岁雌性犬发生的伴有显著间质骨化的成釉细胞瘤罕见病例进行了研究。右侧下颌第一磨牙区域出现一个骨块，且迅速复发。组织病理学检查显示该病变为成釉细胞瘤的一种非典型变体。上皮细胞表现出明显的细胞异型性，有丝分裂象相当常见。胶原性间质丰富，有由活跃成骨细胞包绕的骨小梁显著形成。该肿瘤增殖性高且具有侵袭性，被认为本质上是恶性的。
