Niebrj-Dobosz I, Rowińska-Marcińska K, Dembek I
Neurol Neurochir Pol. 1977 Jul-Aug;11(4):427-34.
The material reported includes 14 patients with a history of Guillain-Barré syndrome of relatively mild course many years ago. No abnomalities were found in them on neurological examination. Electrophysiological investigations of peripheral nerves revealed, however, changes indicating slight but persistent subclinical lesions. Conduction changes involved the sensory and motor fibres in the tested nerves and were most evident in the ulnar nerve. Changes of maximal motor conduction velocity were , apart from some cases, parallel to the changes in the minimal conduction velocity. Late subclinical sequelae in this group were compared with those in a group of cases with severe course of the disease and no significant differences were disclosed. It seems thus that the electrophysiological sequelae are not relevant to the clinical pattern of the acute stage and may persist even after the mildest form of the syndrome without evidence of any clinical abnormalities.
报告的病例包括14例多年前患过病程相对较轻的吉兰-巴雷综合征的患者。神经系统检查未发现他们有任何异常。然而,对周围神经的电生理检查显示有变化,表明存在轻微但持续的亚临床病变。传导变化涉及受试神经的感觉和运动纤维,在尺神经中最为明显。除某些病例外,最大运动传导速度的变化与最小传导速度的变化平行。将该组的晚期亚临床后遗症与一组疾病病程严重的病例进行比较,未发现显著差异。因此,电生理后遗症似乎与急性期的临床类型无关,即使在综合征最轻微的形式之后也可能持续存在,且无任何临床异常迹象。