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某些喹诺酮类抗生素的电化学研究。第二部分。原料药及药物制剂中差示脉冲极谱法的测定

Electrochemical studies of some quinolone antibiotics. Part II. Determination by differential pulse polarography in substance and in pharmaceutical formulations.

作者信息

Warowna-Grześkiewicz M, Chodkowski J, Fijałek Z

机构信息

Department of Inorganic and Analytical Chemistry, Warsaw School of Medicine, Poland.

出版信息

Acta Pol Pharm. 1995 Nov-Dec;52(6):441-5.

PMID:8960262
Abstract

Differential pulse polarography was used to study quinolone antibiotics: ciprofloxacin, enoxacin, norfloxacin, ofloxacin and pefloxacin on a mercury electrode. The optimal parameters and background solutions have been chosen. New polarographic method of quinolone determination in pure form and pharmaceutical formulations was found. Statistical analysis of the results obtained showed that proposed method is of good accuracy and precision.

摘要

采用差分脉冲极谱法在汞电极上研究喹诺酮类抗生素

环丙沙星、依诺沙星、诺氟沙星、氧氟沙星和培氟沙星。选择了最佳参数和背景溶液。建立了测定纯品和药物制剂中喹诺酮类的新极谱方法。对所得结果的统计分析表明,所提出的方法具有良好的准确度和精密度。

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