Tzivoni D
Department of Cardiology, Jesselson Heart Center, Shaare Zedek Medical Center, Jerusalem, Israel.
Eur Heart J. 1996 Dec;17 Suppl G:59-63. doi: 10.1093/eurheartj/17.suppl_g.59.
Myocardial ischaemia in daily life varies according to a circadian rhythm and is induced by many factors, including both increased myocardial oxygen demand and changes in coronary tone. In most patients, ischaemia is induced by a combination of different contributing factors, although the relative contribution of each mechanism varies from patient to patient. Moreover, in the same individual, various episodes may be due to different mechanisms. The relative contributions of increased myocardial oxygen demand and decreased ischaemic threshold to the development of ischaemia in daily life can be assessed by continuous ambulatory ECG monitoring which may help to optimize medical anti-ischaemic therapy.
日常生活中的心肌缺血根据昼夜节律而变化，并且由多种因素诱发，包括心肌需氧量增加和冠状动脉张力改变。在大多数患者中，缺血是由不同促成因素共同作用诱发的，尽管每种机制的相对作用因患者而异。此外，在同一个体中，不同发作可能由不同机制导致。通过连续动态心电图监测可以评估日常生活中心肌需氧量增加和缺血阈值降低对缺血发生的相对作用，这可能有助于优化抗缺血药物治疗。
