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Lack of association between alpha 1-antichymotrypsin polymorphism, Alzheimer's disease, and allele epsilon 4 of apolipoprotein E.

作者信息

Müller U, Bödeker R H, Gerundt I, Kurz A

机构信息

Institut für Humangenetik, Justus-Liebig-Universität, Giessen, Germany.

出版信息

Neurology. 1996 Dec;47(6):1575-7. doi: 10.1212/wnl.47.6.1575.

DOI:10.1212/wnl.47.6.1575
PMID:8960749
Abstract

We investigated the possibility that a polymorphism of alpha 1-antichymotrypsin modifies the risk for Alzheimer's disease (AD). Testing 147 AD patients and 74 controls, we did not find evidence of an association between alpha 1-antichymotrypsin polymorphism and AD and also failed to detect a modifying effect of this polymorphism in patients carrying at least one epsilon 4 allele of apolipoprotein E.

摘要

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1
Lack of association between alpha 1-antichymotrypsin polymorphism, Alzheimer's disease, and allele epsilon 4 of apolipoprotein E.
Neurology. 1996 Dec;47(6):1575-7. doi: 10.1212/wnl.47.6.1575.
2
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9
[The relation between alpha1-antichymotrypsin gene polymorphism and epsilon4 allele of apolipoprotein E gene in Alzheimer disease in Chinese].[中国阿尔茨海默病患者中α1-抗糜蛋白酶基因多态性与载脂蛋白E基因ε4等位基因的关系]
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10
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