Perkins R P
Obstet Gynecol. 1977 Sep;50(3):370-2.
Intrigued by the potential simplicity and far-reaching benefits of the amelioration or prevention of gestational diabetes mellitus by pyridoxine, as reported by others, an attempt to confirm this effect was made. No beneficial effects on abnormal glucose tolerance in pregnancy was demonstrated in 4 cases studied. It is likely that the dietary alterations made during pyridoxine therapy in the previous report had a greater effect on outcome than the authors had suspected. The failure to confirm their results was statistically significant (P = 0.005).
受其他人报道的吡哆醇改善或预防妊娠糖尿病可能具有的简便性和深远益处的启发,我们进行了一项旨在证实这种效果的尝试。在所研究的4例病例中,未发现对妊娠期间异常糖耐量有有益影响。在前一份报告中,吡哆醇治疗期间的饮食改变可能对结果产生了比作者所怀疑的更大的影响。未能证实他们的结果在统计学上具有显著意义(P = 0.005)。