Citrome L, Levine J, Allingham B
Nathan Kline Institute, Orangeburg, NY 10962, USA.
Psychopharmacol Bull. 1996;32(3):321-6.
This report describes the extent and pattern of use of depot neuroleptics within the 21 adult civil psychiatric hospitals operated by the New York State Office of Mental Health (OMH). All inpatients receiving depot or oral neuroleptics in calendar year 1994 were identified. In addition to descriptive data on admission and drug orders, a logistic regression was fit using gender, age, race, and facility for the probability of receiving depot. Depot utilization ranged from 12 percent to 39 percent of all patients receiving neuroleptics (N = 18,543). Differences among facilities were statistically significant (p < .05). Gender was not found to be a statistically significant factor, but blacks and Hispanic/others were found to be more likely than whites to receive depot (p < .05), and those 65 years or older were found to be less likely to receive depot (p < .05). For patients admitted in 1994, depot neuroleptics were typically started within a month or two of admission and continued for 2 to 3 months, with 86 percent of these patients discharged by December 31, 1995. Except for milligram dose and frequency of injection, haloperidol decanoate and fluphenazine decanoate did not differ in terms of extent and pattern of use.
本报告描述了纽约州心理健康办公室（OMH）运营的21家成人民事精神病医院中长效抗精神病药物的使用范围和模式。确定了1994年接受长效或口服抗精神病药物治疗的所有住院患者。除了关于入院和药物医嘱的描述性数据外，还使用性别、年龄、种族和医疗机构作为接受长效药物治疗概率的自变量进行了逻辑回归分析。长效药物的使用占所有接受抗精神病药物治疗患者（N = 18,543）的12%至39%。各医疗机构之间的差异具有统计学意义（p < .05）。未发现性别是一个具有统计学意义的因素，但发现黑人和西班牙裔/其他种族的患者比白人更有可能接受长效药物治疗（p < .05），而65岁及以上的患者接受长效药物治疗的可能性较小（p < .05）。对于1994年入院的患者，长效抗精神病药物通常在入院后一两个月内开始使用，并持续2至3个月，其中86%的患者在1995年12月31日前出院。除了毫克剂量和注射频率外，癸酸氟哌啶醇和癸酸氟奋乃静在使用范围和模式方面没有差异。
