Khovanskikh A E, Krylov M V, Mikhaĭlov G A, Mishin V S, Krylova N P
Parazitologiia. 1977 Jul-Aug;11(4):353-60.
The infection of chicks with optimal immunogenic doses of oocysts of E. tenella and E. acervulina results in the activation of biosynthesis of proteins and nucleic acids in the Fabricius bursa, spleen, thymus and blind processes of the intestine. The infection causes the increase in the quantity and synthesis intensity of immunoglobulins G and M that suggests a stimulation of cellular and immunity factors in the ogranism of an immunized bird. Maximum changes in biosynthesis of compounds studied are reported four days after the infection that confirms high immunogenic properties of the second generation schizonts. A study of protein synthesis in limphoid organs of chicks infected only with E. tenella has yielded the same results. The infection with E. acervulina caused but negligible changes in the protein metabolism, i.e. coccidians of E. tenella possess more immunogenic properties.
用最佳免疫原剂量的柔嫩艾美耳球虫和堆型艾美耳球虫卵囊感染雏鸡，会导致法氏囊、脾脏、胸腺和肠道盲突中蛋白质和核酸生物合成的激活。这种感染会使免疫球蛋白G和M的数量及合成强度增加，这表明免疫鸡体内的细胞和免疫因子受到了刺激。在感染后四天报告了所研究化合物生物合成的最大变化，这证实了第二代裂殖体具有高免疫原性。对仅感染柔嫩艾美耳球虫的雏鸡淋巴器官中蛋白质合成的研究也得出了相同的结果。堆型艾美耳球虫感染引起的蛋白质代谢变化可忽略不计，即柔嫩艾美耳球虫的球虫具有更强的免疫原性。
