Alvarez-Sala R, Prados C, de Miguel E, García-Talavera I, Muñoz J
Servicio de Neumología, Hospital La Paz, Universidad Autónoma, Madrid.
An Med Interna. 1996 Jul;13(7):339-40.
Histiocytosis X is considered a group of diseases of unknown origin. Nevertheless, the presence of certain lymphocytes disorders and immunocomplexes has permitted us to think that it is an immunologic disease. The ankylosing spondylitis is also a disease of unknown origin, but like the histiocytosis X, might be of immunologic origin. In both entities, a defect of T-lymphocytes has been demonstrated. We present a patient in whom both diseases are associated, which is not reported before in the medical literature. We think that these disorders may be related by a common immunologic alteration.
组织细胞增多症X被认为是一组病因不明的疾病。然而,某些淋巴细胞紊乱和免疫复合物的存在使我们认为它是一种免疫性疾病。强直性脊柱炎也是一种病因不明的疾病,但与组织细胞增多症X一样,可能起源于免疫方面。在这两种疾病中,均已证实存在T淋巴细胞缺陷。我们报告一位同时患有这两种疾病的患者,医学文献中此前未见此类报道。我们认为这些疾病可能因一种共同的免疫改变而相关。