Mörsch C, Höh H R
Augenklinik der Universität des Saarlandes, Homburg/Saar.
Ophthalmologe. 1996 Aug;93(4):404-12.
No adequate research results are available on the frequency and medical significance of intraindividual side differences in the entoptic functions and interference fringe acuity. We have collected data on these topics from examinations of 312 people with no eye defects; the subjects in this group were aged between 6 and 85 years and were divided into ten age-groups of approximately the same size. We were trying to find out to what extent a real side difference in the distant or near visual acuity can be deduced from an intraindividual side difference in the entoptic function test and/or laser interferometry as in healthy people. To allow grading of macular chagrin patches for the first time we defined the "microsymptoms of macular chagrin" patches. Moreover, we described the changes in interference fringe acuity and in entoptic function with advancing age. By using already established research approaches, we have evaluated the following parameters of examination: distant visual acuity with optotypes, near visual acuity (Nieden), entoptic functions (vessel figure of Purkinje and macular chagrin patches), laser interferometry (Retinometer) and ophthalmological findings. We found that of macular chagrin varied in appearance with the age of the patient. Patients with no eye defects seldom have an intraindividual side difference in the distant or near visual acuity, and any present is only marginal. This is why there seems to be too narrow a correlation with the results of the laser interferometry and of the entoptic function test. The negative predictive value is between 89% and 95%. This means that patients who have no side difference in interference fringe acuity or in the entoptic function test also have no intraindividual side difference in distant visual acuity with optotypes or near visual acuity (Nieden). This is the medical significance of our results in respect to more marked side differences such as are found in patients with eye defects. The predictive significance of the entoptic function test is enhanced by knowledge of microsymptoms of macular chagrin patches.
关于个体内部视内功能和干涉条纹敏锐度的侧别差异的频率及医学意义，目前尚无充分的研究结果。我们从312名无眼部缺陷的人的检查中收集了关于这些主题的数据；该组受试者年龄在6岁至85岁之间，被分为十个大小大致相同的年龄组。我们试图弄清楚，在健康人群中，从视内功能测试和/或激光干涉测量的个体内部侧别差异中，能在多大程度上推断出远视力或近视力的实际侧别差异。为了首次能够对视盘小凹斑进行分级，我们定义了“视盘小凹的微症状”斑。此外，我们描述了干涉条纹敏锐度和视内功能随年龄增长的变化。通过使用已确立的研究方法，我们评估了以下检查参数：用视力表检查的远视力、近视力（尼登视力）、视内功能（浦肯野血管图像和视盘小凹斑）、激光干涉测量（视网膜计）以及眼科检查结果。我们发现视盘小凹的外观随患者年龄而变化。无眼部缺陷的患者在远视力或近视力方面很少有个体内部侧别差异，即便有也很微小。这就是为什么它与激光干涉测量结果和视内功能测试结果之间的相关性似乎很弱。阴性预测值在89%至95%之间。这意味着在干涉条纹敏锐度或视内功能测试中没有侧别差异的患者，在用视力表检查的远视力或近视力（尼登视力）方面也没有个体内部侧别差异。就眼部有缺陷的患者中发现的更明显的侧别差异而言，这就是我们研究结果的医学意义。对视盘小凹斑微症状的了解增强了视内功能测试的预测意义。
